ArticleJournal of Crohn's & colitis2014
Risk factors for depression in the elderly inflammatory bowel disease population.
Article in Journal of Crohn's & colitis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Socioeconomic status and depression-a systematic review.Epidemiologic reviews · 2025Pooled it
- Ulcerative colitis (UC) in the elderly: diagnostic and therapeutic considerations.Frontiers in aging · 2026Review
- Medication Non-Adherence in Inflammatory Bowel Disease: A Systematic Review Identifying Risk Factors and Opportunities for Intervention.Pharmacy (Basel, Switzerland) · 2025Review
- Exploring the management and treatment of IBD from the perspective of psychological comorbidities.Therapeutic advances in gastroenterology · 2024Review
- The Impact of COVID-19 on Health Anxiety and Perceived Stress Among Persons with IBD: A Population-representative Study.Journal of the Canadian Association of Gastroenterology · 2023Article
- Polygenic risk and causal inference of psychiatric comorbidity in inflammatory bowel disease among patients with European ancestry.Journal of translational medicine · 2022Article
- Article
- Microbiota-gut-brain axis and its affect inflammatory bowel disease: Pathophysiological concepts and insights for clinicians.World journal of clinical cases · 2020Review
- Depressive symptoms in inflammatory bowel disease: an extraintestinal manifestation of inflammation?Clinical and experimental immunology · 2019Review
- Management of elderly ulcerative colitis in Japan.Journal of gastroenterology · 2019Review
- High Patient Activation Is Associated With Remission in Patients With Inflammatory Bowel Disease.Inflammatory bowel diseases · 2019Article
- Inflammatory Bowel Disease in the Baby to Baby Boomer: Pediatric and Elderly Onset of IBD.Current treatment options in gastroenterology · 2018Review
- Psychiatric morbidity in inflammatory bowel disease: Time to screen all the patients.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2018Article
- Depression Is Associated With More Aggressive Inflammatory Bowel Disease.The American journal of gastroenterology · 2018Article
- Article
- Healthcare maintenance in elderly patients with inflammatory bowel disease.Annals of gastroenterology · 2017Review
- Achieving Synergy: Linking an Internet-Based Inflammatory Bowel Disease Cohort to a Community-Based Inception Cohort and Multicentered Cohort in Inflammatory Bowel Disease.Journal of medical Internet research · 2016Article
- Influence of environmental factors in the development of inflammatory bowel diseases.World journal of gastrointestinal pharmacology and therapeutics · 2016Review
- Challenges in the Diagnosis and Management of Inflammatory Bowel Disease in the Elderly.Current treatment options in gastroenterology · 2015Article
- Psychological status in Iranian patients with ulcerative colitis and its relation to disease activity and quality of life.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
BACKGROUND AND
aimsLittle is known about depression in elderly individuals with inflammatory bowel diseases (IBD). We assessed the point prevalence of depression and determined associations with disease activity, quality of life, and medication adherence in elderly patients with IBD.
methodsWe identified elderly (≥ 65 years) individuals within Crohn's and Colitis Foundation of America Partners, an online IBD cohort. Individuals completed the short geriatric depression scale (GDS). We used bivariate statistics to determine whether demographic or disease-related factors, disease activity, quality of life or medication adherence was associated with depression. We used logistic regression to estimate independent effects of depression on medication adherence.
resultsA total of 359 elderly individuals with IBD completed the GDS. The mean age was 70.2 years (SD 4.7); mean disease duration was 25.6 years (SD 17.6), and 62.6% had Crohn's disease (CD). The point prevalence of depression was 22.6%. Lower education levels (p=0.001), higher corticosteroid use (<0.01) and lower exercise levels (<0.001) were associated with depression. For both CD and ulcerative colitis (UC), those with depression had increased disease activity (short Crohn's disease activity index 52.5 versus 29, p=0.005, and simple clinical colitis activity index 5 versus 2, p=0.003). Depressed patients had lower quality of life (short IBD questionnaire 4.6 versus 5.7, p<0.001). Depressed individuals had reduced medication adherence (adjusted OR 2.18; 95% CI 1.04-4.57).
conclusionsDepression is common in this geriatric IBD cohort. Depression is independently associated with reduced medication adherence. Recognition and treatment of depression in elderly patients with IBD could improve outcomes.
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