Evidence map›Paper›PMID 23932458›Full record

Trial reportThe Journal of allergy and clinical immunology2014

Validation and psychometric properties of the Asthma Control Questionnaire among children.

Jessica M Nguyen, Janet T Holbrook, Christine Y Wei, Lynn B Gerald, W Gerald Teague, Robert A Wise, American Lung Association Asthma Clinical Research Centers

Open access · hybridAbstract readClinical TrialMulticenter StudyValidation Study
In one paragraph

Trial report in The Journal of allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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  11. Influence of parental anxiety and beliefs about medicines on feeding and exercise in children living with asthma.Journal of child health care : for professionals working with children in the hospital and community · 2024
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  14. Review
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  20. Parental Feeding, Child Eating and Physical Activity: Differences in Children Living with and without Asthma.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jessica M NguyenDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Md.
Janet T HolbrookDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Md.
Christine Y WeiDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Md.
Lynn B GeraldDepartment of Health Promotion Sciences, University of Arizona College of Public Health, Tucson, Ariz.
W Gerald TeagueDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, Va.
Robert A WiseDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Md. Electronic address: rwise@jhmi.edu.
American Lung Association Asthma Clinical Research Centers
Johns Hopkins Medicine · USJohns Hopkins University · USUniversity of Arizona · USUniversity of Virginia · US

Funding

Airway redox biochemistry as a deteriminant of asthma phenotype during adolescen*U10HL109250 · NHLBI · UNIVERSITY OF VIRGINIA · PI ERZURUM, SERPIL C., GASTON, BENJAMIN · 2011 to 2016
$4.2M
Study of Acid Reflux Therapy for Children with AsthmaU01HL080450 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HOLBROOK, JANET T. · 2006 to 2010
$2.3M
Study of Acid Reflux Therapy for Children with AsthmaU01HL080433 · NHLBI · UNIVERSITY OF VIRGINIA · PI TEAGUE, WILLIAM GERALD · 2006 to 2010
$1.8M
NHLBI NIH HHS U01 HL080433NHLBI NIH HHS U01 HL080450NHLBI NIH HHS U10 HL109250
6 · The paper itself

Abstract

backgroundThe Asthma Control Questionnaire (ACQ) is a patient-centered tool for evaluating asthma control. It has been validated in adults, but not well-validated among children.

objectiveWe evaluated the reliability, validity, and responsiveness to change of the ACQ for assessing asthma control in children ages 6 to 17 years. A threshold value for poor disease control and a minimally important difference were also determined.

methodsData from 305 asthmatic children enrolled in a clinical trial were examined. The ACQ was administered at 8 visits. We analyzed results for the combined age group and for the 6- to 11-year-old and 12- to 17-year-old age groups separately.

resultsOverall, the Cronbach α value (internal consistency) for the ACQ was 0.74 at baseline, and the intraclass correlation coefficient (test-retest reliability) for repeated questionnaires among stable patients was 0.53. The Pearson correlations between the ACQ and other asthma questionnaires were moderate to strong (-0.64 to -0.73). Mean ACQ scores were higher (worse) in patients whose peak flow decreased, who used more rescue medications, or who sought medical care for asthma than in patients who were stable (P < .0001 for all measures). Changes in ACQ scores were significantly different among patients with deteriorating, improving, or stable asthma symptoms (P ≤ .01). The optimal threshold indicating poor asthma control was 1.25 or greater. The minimally important difference was established to be 0.40. Results for the separate age groups were similar.

conclusionThe ACQ is a moderately reliable, valid, and responsive tool with adequate psychometric properties for assessing recent asthma control among children.

Indexed as

AdolescentAsthmaChildCohort StudiesFemaleHumansInfantMalePremature BirthPsychometricsQuality of LifeReproducibility of ResultsSurveys and QuestionnairesACQACTAsthmaasthma controlAsthma Control QuestionnaireAsthma Control TestAsthma Symptom Utility IndexASUIcACTChildhood Asthma Control TestEPACEpisode of poor asthma controlICCIntraclass correlation coefficientMIDminimally important differenceMinimally important differencepAQLQPeak expiratory flow ratePediatric Asthma Quality of Life QuestionnairePEFRReceiver operating characteristicROCvalidity

Identifiers

PMID23932458
PMCPMC3874246
OpenAlexW2070950938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.