ArticleThe primary care companion for CNS disorders2013
Depression and chronic diseases: it is time for a synergistic mental health and primary care approach.
Article in The primary care companion for CNS disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- The Association Between Nut Consumption and Risk of Depressive Symptoms: A Meta-Analysis of Observational Studies.Nutrients · 2025Pooled it
- Elucidating the bidirectional association between autoimmune diseases and depression: a systematic review and meta-analysis.BMJ mental health · 2024Pooled it
- The prevalence of depression in patients living with implantable cardioverter defibrillator: a systematic review and meta-analysis.Irish journal of medical science · 2020Pooled it
- Modelling the Associations Between the Physician-Patient Relationship and Patient Outcomes via Self-Determination Theory Variables in Chronic Disease Management.International journal of behavioral medicine · 2026Article
- Mental health treatment experiences before, during, and after incarceration: Perspectives of formerly incarcerated Black men.Psychological services · 2026Article
- Comorbidity patterns of chronic respiratory diseases in older Chinese adults: A repeated cross-sectional study from CHARLS.Medicine · 2026Article
- The Role of Associated Treatment Factors and Mental Health on Transition From Pediatric to Adult Care for Adolescent/Young Adults With Sickle Cell Disease.Pediatric blood & cancer · 2026Article
- Molecular Mechanisms of Depression: The Interplay Between Genes and Receptors.International journal of molecular sciences · 2025Review
- Observational
- Depressive symptoms and associated factors among patients with diabetes in public primary healthcare facilities in Kuwait city, 2024.Scientific reports · 2025Article
- Depressive symptoms among resettled Bhutanese older adults in Ohio: a cross-sectional study.BMC psychology · 2025Article
- The association between metabolic associated fatty liver disease and depression in adults: the role of physical activity levels and types.Archives of medical science : AMS · 2025Article
- The relationship between family conflict resolution methods and depressive symptoms in patients with chronic diseases.PloS one · 2025Article
- Multi-target approach of Egyptian leek extract in ameliorating depressive-like behavior in rats exposed to chronic unpredictable mild stress.Frontiers in pharmacology · 2025Article
- Barriers and facilitators to integrating the friendship bench into non-communicable disease care in Malawi: A qualitative study.PLOS mental health · 2025Article
- The association of triglyceride glucose waist-to-height ratio index with depression in United States adults.Frontiers in nutrition · 2025Article
- Association between atherogenic index of plasma and depression in individuals with different glucose metabolism status.Frontiers in psychiatry · 2025Article
- Insufficient Evidence to RecommendNeuropsychiatric disease and treatment · 2025Review
- The relationship between mental health problems and risk of infectious diseases: A Mendelian randomization analysis.Medicine · 2024Article
- Comorbid physical health burden of serious mental health disorders in 32 European countries.BMJ mental health · 2024Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify the growing significance of depression as a global leading cause of years lost to disability and its role as a major independent risk factor in many chronic illnesses. The distinct effects of depression on morbidity and mortality in cancer, diabetes, heart disease, and stroke are investigated, including behavioral factors and plausible biological mechanisms (psychoneuroimmunology of depression). DATA SOURCES: PubMed articles in English were searched from 1992 to 2012 (20-year span) using the following search criteria: psychoneuroimmunology of depression, immune-mediated inflammation, depression treatment recommendations, depression screening, years lost to disability, underserved populations and depression, chronic illnesses and depression, and selective serotonin reuptake inhibitors and immune system. DATA SYNTHESIS: Evidence of the robust bidirectional relationship between depression and individual chronic diseases is presented and discussed. A brief overview of currently recommended psychotherapeutic and psychopharmacologic treatment approaches in regard to depression in chronic diseases is provided.
resultsDiscordance between mental health and primary care within the US public health system is a systematic problem that must be addressed. This situation leads to a potentially high hidden prevalence of underdiagnosed and undertreated depression, especially in the underserved populations.
conclusionMeasures must be implemented across the communities of mental health and primary care practitioners in order to achieve a synergistic approach to depression.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.