ArticleAmerican journal of human genetics1990
Genes for two autosomal recessive forms of chronic granulomatous disease assigned to 1q25 (NCF2) and 7q11.23 (NCF1).
Article in American journal of human genetics, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 76 citations in OpenAlex.
- Clinical, Immunological, and Molecular Findings of Patients with p47Journal of clinical immunology · 2016Article
- Regulation of CDX4 gene transcription by HoxA9, HoxA10, the Mll-Ell oncogene and Shp2 during leukemogenesis.Oncogenesis · 2014Article
- Molecular identification of bacterial DNA in the chorioretinal scars of chronic granulomatous disease.Journal of clinical immunology · 2013Article
- Article
- A copy number variation in human NCF1 and its pseudogenes.BMC genetics · 2010Article
- Genetics and immunopathology of chronic granulomatous disease.Seminars in immunopathology · 2008Review
- Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.Genome research · 2002Article
- Chronic granulomatous disease.Clinical and experimental immunology · 2000Review
- Comparative mapping of the region of human chromosome 7 deleted in williams syndrome.Genome research · 1999Article
- The molecular basis of chronic granulomatous disease.Springer seminars in immunopathology · 1998Review
- A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease.The Journal of clinical investigation · 1997Article
- Mechanisms for the activation/electron transfer of neutrophil NADPH-oxidase complex and molecular pathology of chronic granulomatous disease.Annals of hematology · 1994Review
- Cloning and functional expression of the mouse homologue of p47phox.Immunogenetics · 1994Article
- Identification of a thermolabile component of the human neutrophil NADPH oxidase. A model for chronic granulomatous disease caused by deficiency of the p67-phox cytosolic component.The Journal of clinical investigation · 1992Article
- Mouse chromosome 1.Mammalian genome : official journal of the International Mammalian Genome Society · 1992Review
- Mouse chromosome 13.Mammalian genome : official journal of the International Mammalian Genome Society · 1992Review
- Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1992Review
- Mouse chromosome 1.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
- Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
- Functional pseudogenes inhibit the superoxide production.Precision medicineArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Chronic granulomatous disease (CGD) is a heterogeneous group of inherited disorders of impaired superoxide production in phagocytes. The most common X-linked recessive form involves the CYBB locus in band Xp21.1 that encodes the membrane-bound beta subunit of the cytochrome b558 complex. Two autosomal recessive forms of CGD result from defects in cytosolic components of the phagocyte NADPH oxidase system, p47phox (NCF1) and p67phox (NCF2). By using human cDNA probes we have mapped the genes for these proteins to chromosomal sites. The combined data from Southern analysis of somatic cell hybrid lines and chromosomal in situ hybridization localize NCF1 to 7q11.23 and NCF2 to band 1q25. The NCF1 localization corrects an erroneous preliminary assignment to chromosome 10. In the mouse, the locus corresponding to NCF2 (Ncf-2) was mapped with somatic cell hybrid panels and recombinant inbred strains to mouse chromosome 1 near Xmv-21 within a region of conserved homology with human chromosome 1 region q21-q32. A second site, probably a processed pseudogene, was identified on mouse chromosome 13.
Indexed as
Identifiers
2393022PMC1683885W1543005717What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.