Evidence map›Paper›PMID 23930154›Full record

ArticleThe journal of physical chemistry letters2013

Labeling Cytosolic Targets in Live Cells with Blinking Probes.

Jianmin Xu, Jason Chang, Qi Yan, Thomas Dertinger, Marcel Bruchez, Shimon Weiss

Open access · greenAbstract read
In one paragraph

Article in The journal of physical chemistry letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
7.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Small fluorescence-activating and absorption-shifting tag for tunable protein imaging in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  2. Review
  3. Localization microscopy using noncovalent fluorogen activation by genetically encoded fluorogen-activating proteins.Chemphyschem : a European journal of chemical physics and physical chemistry · 2014
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jianmin XuDepartment of Chemistry & Biochemistry, University of California Los Angeles, Los Angeles CA 90095.
Jason Chang
Qi Yan
Thomas Dertinger
Marcel Bruchez
Shimon Weiss
Sharp Edge Labs (United States) · USUniversity of California, Los Angeles · US

Funding

New Probe and Methods for Correlated LM & EMR01GM086197 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ADAMS, STEPHEN ROY, BOASSA, DANIELA · 2008 to 2020
$8.3M
Multimodal Qdot Probes for Bioimaging of Cells and Tumors in Small AnimalsR01EB000312 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WEISS, SHIMON · 2002 to 2010
$7.5M
Bright Blinking Probes for Fast Multicolor Superresolution Imaging in Live CellsR01GM086237 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI BRUCHEZ, MARCEL P · 2009 to 2010
$347k
NIBIB NIH HHS R01 EB000312NIGMS NIH HHS R01 GM086197NIGMS NIH HHS R01 GM086237
6 · The paper itself

Abstract

With the advent of superresolution imaging methods, fast dynamic imaging of biological processes in live cells remains a challenge. A subset of these methods requires the cellular targets to be labeled with spontaneously blinking probes. The delivery and specific targeting of cytosolic targets and the control of the probes' blinking properties are reviewed for three types of blinking probes: quantum dots, synthetic dyes, and fluorescent proteins.

Indexed as

Fluorescent proteinsOptical nanoscopyQuantum dotsSingle molecule localization microscopySuperresolution imagingSynthetic dyes

Identifiers

PMID23930154
PMCPMC3733402
OpenAlexW2036911324

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.