Evidence map›Paper›PMID 23929894›Full record

SynthesisBMJ (Clinical research ed.)2013

Perceived job insecurity as a risk factor for incident coronary heart disease: systematic review and meta-analysis.

Marianna Virtanen, Solja T Nyberg, G David Batty, Markus Jokela, Katriina Heikkilä, Eleonor I Fransson, Lars Alfredsson, Jakob B Bjorner, Marianne Borritz, Hermann Burr and 38 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ (Clinical research ed.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Work-related stress as a cardiovascular risk factor in police officers: a systematic review of evidence.International archives of occupational and environmental health · 2018
    Pooled it
  5. Job insecurity and risk of diabetes: a meta-analysis of individual participant data.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2016
    Pooled it
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

48 authors.

Marianna VirtanenFinnish Institute of Occupational Health, FI-00250 Helsinki, Finland. marianna.virtanen@ttl.fi
Solja T Nyberg
G David Batty
Markus Jokela
Katriina Heikkilä
Eleonor I Fransson
Lars Alfredsson
Jakob B Bjorner
Marianne Borritz
Hermann Burr
Annalisa Casini
Els Clays
Dirk De Bacquer
Nico Dragano
Marko Elovainio
Raimund Erbel
Jane E Ferrie
Mark Hamer
Karl-Heinz Jöckel
France Kittel
Anders Knutsson
Markku Koskenvuo
Aki Koskinen
Thorsten Lunau
Ida E H Madsen
Martin L Nielsen
Maria Nordin
Tuula Oksanen
Krista Pahkin
Jan H Pejtersen
Jaana Pentti
Reiner Rugulies
Paula Salo
Martin J Shipley
Johannes Siegrist
Andrew Steptoe
Sakari B Suominen
Töres Theorell
Salla Toppinen-Tanner
Ari Väänänen
Jussi Vahtera
Peter J M Westerholm
Hugo Westerlund
Natalie Slopen
Ichiro Kawachi
Archana Singh-Manoux
Mika Kivimäki
IPD-Work Consortium

Funding

Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
Health behaviors over the adult lifecourse and cognitive agingR01AG034454 · NIA · UNIVERSITY COLLEGE LONDON · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2009 to 2013
$1.5M
British Heart Foundation RG/10/005/28296British Heart Foundation RG/13/2/30098Medical Research Council K013351Medical Research Council MR/K013351/1NHLBI NIH HHS R01HL036310NIA NIH HHS R01AG034454Wellcome Trust
6 · The paper itself

Abstract

objectiveTo determine the association between self reported job insecurity and incident coronary heart disease.

designA meta-analysis combining individual level data from a collaborative consortium and published studies identified by a systematic review. DATA SOURCES: We obtained individual level data from 13 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. Four published prospective cohort studies were identified by searches of Medline (to August 2012) and Embase databases (to October 2012), supplemented by manual searches. REVIEW

methodsProspective cohort studies that reported risk estimates for clinically verified incident coronary heart disease by the level of self reported job insecurity. Two independent reviewers extracted published data. Summary estimates of association were obtained using random effects models.

resultsThe literature search yielded four cohort studies. Together with 13 cohort studies with individual participant data, the meta-analysis comprised up to 174,438 participants with a mean follow-up of 9.7 years and 1892 incident cases of coronary heart disease. Age adjusted relative risk of high versus low job insecurity was 1.32 (95% confidence interval 1.09 to 1.59). The relative risk of job insecurity adjusted for sociodemographic and risk factors was 1.19 (1.00 to 1.42). There was no evidence of significant differences in this association by sex, age (<50 v ≥ 50 years), national unemployment rate, welfare regime, or job insecurity measure.

conclusionsThe modest association between perceived job insecurity and incident coronary heart disease is partly attributable to poorer socioeconomic circumstances and less favourable risk factor profiles among people with job insecurity.

Indexed as

Coronary DiseaseEuropeFemaleHumansIncidenceMalePersonnel DownsizingRisk FactorsSelf ReportStress, PsychologicalUnemployment

Identifiers

PMID23929894
PMCPMC3738256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.