ArticleLab on a chip2013
A PDMS/paper/glass hybrid microfluidic biochip integrated with aptamer-functionalized graphene oxide nano-biosensors for one-step multiplexed pathogen detection.
Article in Lab on a chip, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 287 citations in OpenAlex.
- Translational Barriers and AI-Driven Challenges of Microfluidics-Enabled Wearables and Implantable Systems in Personalized Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Present and future of smart functional materials as actuators in microfluidic devices.Lab on a chip · 2025Review
- Aptamer-Conjugated Magnetic Nanoparticles Integrated with SERS for Multiplex Salmonella Detection.Biosensors · 2025Article
- Microfluidic paper analytic device (μPAD) technology for food safety applications.Biomicrofluidics · 2024Review
- Microfluidics-Based Nanobiosensors for Healthcare Monitoring.Molecular biotechnology · 2024Review
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- Direct Electron Transfer of Glucose Oxidase on Pre-Anodized Paper/Carbon Electrodes Modified through Zero-Length Cross-Linkers for Glucose Biosensors.Biosensors · 2023Article
- Polymeric and Paper-Based Lab-on-a-Chip Devices in Food Safety: A Review.Micromachines · 2023Review
- Future of Nanotechnology in Food Industry: Challenges in Processing, Packaging, and Food Safety.Global challenges (Hoboken, NJ) · 2023Review
- Portable in situ temperature-dependent spectroscopy on a low-cost microfluidic platform integrated with a battery-powered thermofoil heater.View (Beijing, China) · 2023Article
- Microfluidic platforms integrated with nano-sensors for point-of-care bioanalysis.Trends in analytical chemistry : TRAC · 2022Article
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- Nanomaterial-assisted microfluidics for multiplex assays.Mikrochimica acta · 2022Review
- Paper and thread as media for the frugal detection of urinary tract infections (UTIs).Analytical and bioanalytical chemistry · 2022Review
- Recent Advances in Aptasensors For Rapid and Sensitive Detection ofFrontiers in bioengineering and biotechnology · 2022Review
- A novel biosensor based on Blu-ray disc coating film for determination of total amino acid content in tea leaves.RSC advances · 2021Article
- Recent advances in sensitivity enhancement for lateral flow assay.Mikrochimica acta · 2021Review
- Recent innovations in cost-effective polymer and paper hybrid microfluidic devices.Lab on a chip · 2021Review
- Multicolorimetric ELISA biosensors on a paper/polymer hybrid analytical device for visual point-of-care detection of infection diseases.Analytical and bioanalytical chemistry · 2021Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Infectious pathogens often cause serious public health concerns throughout the world. There is an increasing demand for simple, rapid and sensitive approaches for multiplexed pathogen detection. In this paper we have developed a polydimethylsiloxane (PDMS)/paper/glass hybrid microfluidic system integrated with aptamer-functionalized graphene oxide (GO) nano-biosensors for simple, one-step, multiplexed pathogen detection. The paper substrate used in this hybrid microfluidic system facilitated the integration of aptamer biosensors on the microfluidic biochip, and avoided complicated surface treatment and aptamer probe immobilization in a PDMS or glass-only microfluidic system. Lactobacillus acidophilus was used as a bacterium model to develop the microfluidic platform with a detection limit of 11.0 cfu mL(-1). We have also successfully extended this method to the simultaneous detection of two infectious pathogens - Staphylococcus aureus and Salmonella enterica. This method is simple and fast. The one-step 'turn on' pathogen assay in a ready-to-use microfluidic device only takes ~10 min to complete on the biochip. Furthermore, this microfluidic device has great potential in rapid detection of a wide variety of different other bacterial and viral pathogens.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.