ArticleMethods in molecular biology (Clifton, N.J.)2013
Cell senescence culturing methods.
Article in Methods in molecular biology (Clifton, N.J.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Preliminary Data on the Senolytic Effects ofNutrients · 2025Trial
- Trial
- CDK8/19 inhibition prevents adaptive resistance to CDK4/6 inhibitors in vitro and in vivo.Cell reports. Medicine · 2026Article
- Ptychographic analysis of human bone marrow-derived mesenchymal stem cell morphology: The impact of cell senescence.Journal of microscopy · 2025Article
- Single-cell and spatial transcriptomics map senescent vascular cells in arterial remodeling during atherosclerosis in mice.Nature aging · 2025Article
- Comparing the cannabidiol-induced transcriptomic profiles in human and mouse Sertoli cells.Toxicology · 2025Article
- Isolation, Expansion, and Characterization of Rat Hair Follicle Stem Cells and Their Secretome: Insights into Wound Healing Potential.Biomedicines · 2024Article
- Strategies for modeling aging and age-related diseases.npj aging · 2024Review
- Establishment of an immortalized yak granulosa cell line:Frontiers in veterinary science · 2024Article
- Current status and future of gene engineering in livestock.BMB reports · 2024Review
- Targeting the redox system for cardiovascular regeneration in aging.Aging cell · 2023Review
- Cannabidiol-induced transcriptomic changes and cellular senescence in human Sertoli cells.Toxicological sciences : an official journal of the Society of Toxicology · 2023Article
- Cathepsin F is a potential marker for senescent human skin fibroblasts and keratinocytes associated with skin aging.GeroScience · 2023Article
- Effect of Mechanical Loading of Senescent Myoblasts on Their Myogenic Lineage Progression and Survival.Cells · 2022Article
- A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking.Nature aging · 2022Article
- Role of MicroRNAs in acceleration of vascular endothelial senescence.Biochemistry and biophysics reports · 2022Article
- Nuclear Fragility in Radiation-Induced Senescence: Blebs and Tubes Visualized by 3D Electron Microscopy.Cells · 2022Article
- CBX4 Regulates Replicative Senescence of WI-38 Fibroblasts.Oxidative medicine and cellular longevity · 2022Article
- Cdk5 regulatory subunit-associated protein 1 knockout mice show hearing loss phenotypically similar to age-related hearing loss.Molecular brain · 2021Article
- Aging lens epithelium is susceptible to ferroptosis.Free radical biology & medicine · 2021Article
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3 authors.
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Abstract
Development of therapeutic approaches that slow or ablate the adverse physiological and pathological changes associated with aging has been considered as an important goal for gerontological research. As cellular senescence is characterized as the basis for aging in organisms, culturing and subculturing of normal human diploid fibroblasts to mimic the in vivo aging processes have been developed as major methods to investigate molecular events involved in aging. It has been established that normal human diploid fibroblasts can proliferate in culture for only finite periods of time. There are many ways to study aging in vitro. In this chapter, we will discuss some of the basic laboratory procedures for cell senescence culturing methods.
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