ArticleInvestigative ophthalmology & visual science2013
Influence of shape and gradient refractive index in the accommodative changes of spherical aberration in nonhuman primate crystalline lenses.
Article in Investigative ophthalmology & visual science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Quantification of the Anterior-Centripetal Movement of the Ciliary Muscle During Accommodation Using Dynamic OCT Imaging.Translational vision science & technology · 2025Article
- Lens Power and Associated Factors in Nonhuman Primate Subjects: A Cross-sectional Study.Investigative ophthalmology & visual science · 2024Article
- Lens regeneration in humans: using regenerative potential for tissue repairing.Annals of translational medicine · 2020Review
- Single function crystalline lens capable of mimicking ciliary body accommodation.Biomedical optics express · 2020Article
- The Structure of the Lens and Its Associations with the Visual Quality.BMJ open ophthalmology · 2020Review
- Off-axis optical coherence tomography imaging of the crystalline lens to reconstruct the gradient refractive index using optical methods.Biomedical optics express · 2019Article
- System for on- and off-axis volumetric OCT imaging and ray tracing aberrometry of the crystalline lens.Biomedical optics express · 2018Article
- Peripheral Defocus of the Monkey Crystalline Lens With Accommodation in a Lens Stretcher.Investigative ophthalmology & visual science · 2018Article
- The Relationship Between High-Order Aberration and Anterior Ocular Biometry During Accommodation in Young Healthy Adults.Investigative ophthalmology & visual science · 2017Article
- Three-dimensional OCT based guinea pig eye model: relating morphology and optics.Biomedical optics express · 2017Article
- OCT-based full crystalline lens shape change during accommodation in vivo.Biomedical optics express · 2017Article
- Predicting Accommodative Response Using Paraxial Schematic Eye Models.Optometry and vision science : official publication of the American Academy of Optometry · 2016Article
- Full 3-D OCT-based pseudophakic custom computer eye model.Biomedical optics express · 2016Article
- OCT-based crystalline lens topography in accommodating eyes.Biomedical optics express · 2015Article
- Dual band dual focus optical coherence tomography for imaging the whole eye segment.Biomedical optics express · 2015Article
- Measurement of Crystalline Lens Volume During Accommodation in a Lens Stretcher.Investigative ophthalmology & visual science · 2015Article
- Changes in monkey crystalline lens spherical aberration during simulated accommodation in a lens stretcher.Investigative ophthalmology & visual science · 2015Article
- OCT 3-D surface topography of isolated human crystalline lenses.Biomedical optics express · 2014Article
- An analytical method for predicting the geometrical and optical properties of the human lens under accommodation.Biomedical optics express · 2014Article
- Whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography.American journal of ophthalmology · 2014Observational
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeTo estimate changes in surface shape and gradient refractive index (GRIN) profile in primate lenses as a function of accommodation. To quantify the contribution of surface shape and GRIN to spherical aberration changes with accommodation.
methodsCrystalline lenses from 15 cynomolgus monkeys were studied in vitro under different levels of accommodation produced by a stretching system. Lens shape was obtained from optical coherence tomography (OCT) cross-sectional images. The GRIN was reconstructed with a search algorithm using the optical path measured from OCT images and the measured back focal length. The spherical aberration of the lens was estimated as a function of accommodation using the reconstructed GRIN and a homogeneous refractive index.
resultsThe lens anterior and posterior radii of curvature decreased with increasing lens power. Both surfaces exhibited negative asphericities in the unaccommodated state. The anterior surface conic constant shifted toward less negative values with accommodation, while the value of the posterior remained constant. GRIN parameters remained constant with accommodation. The lens spherical aberration with GRIN distribution was negative and higher in magnitude than that with a homogeneous equivalent refractive index (by 29% and 53% in the unaccommodated and fully accommodated states, respectively). Spherical aberration with the equivalent refractive index shifted with accommodation toward negative values (-0.070 μm/diopter [D]), but the reconstructed GRIN shifted it farther (-0.124 μm/D).
conclusionsWhen compared with the lens with the homogeneous equivalent refractive index, the reconstructed GRIN lens has more negative spherical aberration and a larger shift toward more negative values with accommodation.
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