Evidence map›Paper›PMID 23927825›Full record

ArticleJournal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi2015

Impact of bacterial and viral coinfection on mycoplasmal pneumonia in childhood community-acquired pneumonia.

Chih-Yung Chiu, Chih-Jung Chen, Kin-Sun Wong, Ming-Han Tsai, Cheng-Hsun Chiu, Yhu-Chering Huang

Abstract read
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In one paragraph

Article in Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Serum Tumor Necrosis Factor-Canadian respiratory journal · 2018
    Pooled it
  3. Coinfection Patterns ofInternational journal of molecular sciences · 2026
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  12. Azithromycin Effectiveness in Children with MutatedInfection and drug resistance · 2024
    Article
  13. Article
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  15. Article
  16. Adenovirus andFrontiers in pediatrics · 2024
    Article
  17. [Macrolide-resistant Mycoplasma pneumoniae: Do we know the situation in Europe?]Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
    Review
  18. Molecular detection of Mycoplasma pneumoniae in respiratory samples from hospitalized childrenRevista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chih-Yung ChiuDepartment of Pediatrics, Chang Gung Memorial Hospital, Keelung, Taiwan; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan; Division of Pediatric Pulmonology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chih-Jung ChenDivision of Pediatric Infectious Diseases, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Kin-Sun WongDivision of Pediatric Pulmonology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ming-Han TsaiDepartment of Pediatrics, Chang Gung Memorial Hospital, Keelung, Taiwan; Division of Pediatric Infectious Diseases, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Cheng-Hsun ChiuDivision of Pediatric Infectious Diseases, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Yhu-Chering HuangDivision of Pediatric Infectious Diseases, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address: ychuang@adm.cgmh.org.tw.
Chang Gung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeCoinfection of Mycoplasma pneumoniae is not uncommon in children with respiratory syndromes. The purpose of this study was to investigate the impact of bacterial and viral coinfection on mycoplasmal pneumonia in hospitalized children with community-acquired pneumonia (CAP).

methodsChildren coinfected with M. pneumoniae in a prospective study of the etiology of CAP at a tertiary pediatric facility Children's Hospital were enrolled and retrospectively reviewed. The data of clinical characteristics, complications, and outcomes of these children were collected and analyzed.

resultsA total of 59 children were enrolled and stratified into three groups: M. pneumoniae infection alone (n = 31), M. pneumoniae with Streptococcus pneumoniae coinfection (n = 9), and M. pneumoniae with virus coinfection (n = 19). As compared with children infected with M. pneumoniae alone, coinfection of children with S. pneumoniae was more likely to occur under the age of 5 years with a longer duration of fever and hospital stay. Furthermore, total leukocyte count and serum C-reactive protein level were also significantly higher in these children (p < 0.01). However, no significant difference in clinical characteristics, complications, and outcomes was observed between the patients infected with either M. pneumoniae alone or with virus coinfection.

conclusionIn children with CAP, the influence on the clinical outcomes of M. pneumoniae infection may be heavily dependent on the coinfected pathogen. A potential coexistence of M. pneumoniae infection should be considered in children with features suggesting typical bacterial pneumonia.

Indexed as

BacteriaChildChild, PreschoolCoinfectionCommunity-Acquired InfectionsFemaleHumansInfantMalePneumonia, MycoplasmaProspective StudiesStreptococcus pneumoniaeTreatment OutcomeVirus DiseasesVirusesCoinfectionMycoplasma pneumoniaeOutcomes

Identifiers

PMID23927825
OpenAlexW2049518074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.