Evidence map›Paper›PMID 23927516›Full record

ArticleAmerican journal of public health2013

Critical need for family-based, quasi-experimental designs in integrating genetic and social science research.

Brian M D'Onofrio, Benjamin B Lahey, Eric Turkheimer, Paul Lichtenstein

Abstract read
In one paragraph

Article in American journal of public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 192 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
192citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

192 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  9. Preterm birth and mortality in adulthood: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Pooled it
  10. Risk factors for interpersonal violence: an umbrella review of meta-analyses.The British journal of psychiatry : the journal of mental science · 2018
    Pooled it
  11. Parental asthma and risk of autism spectrum disorder in offspring: A population and family-based case-control study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019
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132 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brian M D'OnofrioBrian M. D'Onofrio is with Indiana University, Bloomington. Benjamin B. Lahey is with the University of Chicago, Chicago, IL. Eric Turkheimer is with the University of Virginia, Charlottesville. Paul Lichtenstein is with the Karolinska Institutet, Solna, Sweden.
Benjamin B Lahey
Eric Turkheimer
Paul Lichtenstein

Funding

Quasi-experimental studies of early risk factors for severe psychopathologyR01HD061817 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI D'ONOFRIO, BRIAN M, LICHTENSTEIN, PAUL · 2010 to 2013
$1.3M
Early Causal Risk Factors for Delinquency: Quasi-Experimental TestR01HD061384 · NICHD · UNIVERSITY OF CHICAGO · PI LAHEY, BENJAMIN B · 2010 to 2013
$1.0M
NICHD NIH HHS HD061384NICHD NIH HHS HD061817NICHD NIH HHS R01 HD061384NICHD NIH HHS R01 HD061817
6 · The paper itself

Abstract

Researchers have identified environmental risks that predict subsequent psychological and medical problems. Based on these correlational findings, researchers have developed and tested complex developmental models and have examined biological moderating factors (e.g., gene-environment interactions). In this context, we stress the critical need for researchers to use family-based, quasi-experimental designs when trying to integrate genetic and social science research involving environmental variables because these designs rigorously examine causal inferences by testing competing hypotheses. We argue that sibling comparison, offspring of twins or siblings, in vitro fertilization designs, and other genetically informed approaches play a unique role in bridging gaps between basic biological and social science research. We use studies on maternal smoking during pregnancy to exemplify these principles.

Indexed as

Behavioral ResearchFamily HealthGene-Environment InteractionGenetic ResearchResearch DesignConfounding Factors, EpidemiologicEnvironmental ExposureFemaleHumansPregnancyPregnancy ComplicationsRisk FactorsSmokingSocial Sciences

Identifiers

PMID23927516
PMCPMC3778076

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.