ArticleAmerican journal of public health2013
Defining the environment in gene-environment research: lessons from social epidemiology.
Article in American journal of public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
60 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Trans-Ethnic Meta-Analysis of Interactions Between Genetics and Early-Life Socioeconomic Context on Memory Performance and Decline in Older Americans.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Pooled it
- Does crime trigger genetic risk for type 2 diabetes in young adults? A G x E interaction study using national data.Social science & medicine (1982) · 2022Pooled it
- Underlying Mechanisms of Gene-Environment Interactions in Externalizing Behavior: A Systematic Review and Search for Theoretical Mechanisms.Clinical child and family psychology review · 2015Pooled it
- IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies - An Update.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019Trial
- The long reach of childhood income inequality: a multinational twin study of gene-environment interplay on adult depressive symptoms.Psychological medicine · 2026Article
- Moderating effects of educational inequality on education polygenic scores, attained education and dementia-risk relationships.SSM - population health · 2026Article
- Genetic and environmental influences on alcohol consumption in middle to late life.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025Article
- A Multivariate Genomic Investigation of the Externalizing Spectrum and Suicide Risk.medRxiv : the preprint server for health sciences · 2025Article
- APOE genotype and cognitive decline: educational context as a moderator of genetic risk.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Raising the Floor? Genetic Influences on Educational Attainment Through the Lens of the Evolving Swedish Welfare State.Behavior genetics · 2025Article
- Improving Cardiovascular Health Through the Consideration of Social Factors in Genetics and Genomics Research: A Scientific Statement From the American Heart Association.Circulation. Cardiovascular quality and outcomes · 2025Review
- Interplay between genetic risk and built neighborhood conditions as predictor of BMI across the transition into adulthood.Obesity (Silver Spring, Md.) · 2025Article
- Observational
- Conceptual frameworks for the integration of genetic and social epidemiology in complex diseases.Global epidemiology · 2024Article
- Gene-environment interactions in the influence of maternal education on adolescent neurodevelopment using ABCD study.Science advances · 2024Article
- Shared whole environmental etiology between Alzheimer's disease and age-related macular degeneration.npj aging · 2024Article
- The Human Genome Organisation (HUGO) and a vision for Ecogenomics: the Ecological Genome Project.Human genomics · 2023Review
- Gene-environment interactions and the case of body mass index and obesity: How much do they matter?PNAS nexus · 2023Article
- A population-wide gene-environment interaction study on how genes, schools, and residential areas shape achievement.NPJ science of learning · 2022Article
- How interactions between ADHD and schools affect educational achievement: a family-based genetically sensitive study.Journal of child psychology and psychiatry, and allied disciplines · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
In this article, we make the case that social epidemiology provides a useful framework to define the environment within gene-environment (G × E) research. We describe the environment in a multilevel, multidomain, longitudinal framework that accounts for upstream processes influencing health outcomes. We then illustrate the utility of this approach by describing how intermediate levels of social organization, such as neighborhoods or schools, are key environmental components of G × E research. We discuss different models of G × E research and encourage public health researchers to consider the value of including genetic information from their study participants. We also encourage researchers interested in G × E interplay to consider the merits of the social epidemiology model when defining the environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.