ArticleJournal of reproduction & infertility2012
Effects of pharmaceutical medications on male fertility.
Article in Journal of reproduction & infertility, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 62 citations in OpenAlex.
- The consequences of climate change and male reproductive health: A review of the possible impact and mechanisms.Biochemistry and biophysics reports · 2025Review
- Contraception Requirements in Early Clinical Trials: Considerations Towards an Evidence-Based Approach.Pharmaceutical medicine · 2025Review
- Ameliorative effects of vitamin C and garlic (Frontiers in veterinary science · 2025Article
- Evaluating the Use of Selective Serotonin Reuptake Inhibitors (SSRIs) and Male Infertility: A Critical Retrospective Study.Journal of clinical medicine · 2024Article
- Effects of Pharmaceutical Substances with Obesogenic Activity on Male Reproductive Health.International journal of molecular sciences · 2024Review
- Cisplatin-induced azoospermia and testicular damage ameliorated by adipose-derived mesenchymal stem cells.Biological research · 2023Article
- Effects of autonomic nervous system disorders on male infertility.Frontiers in neurology · 2023Review
- Male Factors: the Role of Sperm in Preimplantation Embryo Quality.Reproductive sciences (Thousand Oaks, Calif.) · 2021Review
- Olanzapine induced reproductive toxicity in male rats.Scientific reports · 2021Article
- Hypertension and reproductive dysfunction: a possible role of inflammation and inflammation-associated lymphangiogenesis in gonads.Clinical science (London, England : 1979) · 2020Review
- Impact of environmental toxin exposure on male fertility potential.Translational andrology and urology · 2020Review
- Herbal remedies used for the treatment of infertility in males and females by traditional healers in the rural areas of the West Bank/Palestine.BMC complementary and alternative medicine · 2019Article
- The forgotten father in obstetric medicine.Obstetric medicine · 2019Review
- Preparation for fatherhood: A survey of men's preconception health knowledge and behaviour in England.PloS one · 2019Article
- Seminal profile of 23,504 patients over the years: 7 years of experience.JBRA assisted reproduction · 2018Article
- Cap-Score™ prospectively predicts probability of pregnancy.Molecular reproduction and development · 2018Observational
- FDA-approved drugs that are spermatotoxic in animals and the utility of animal testing for human risk prediction.Journal of assisted reproduction and genetics · 2018Review
- Toxic Effects of Trazodone on Male Reproductive System via Disrupting Hypothalamic-Pituitary-Testicular Axis and Inducing Testicular Oxidative Stress.Oxidative medicine and cellular longevity · 2018Article
- FDA-approved medications that impair human spermatogenesis.Oncotarget · 2017Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The number of couples seeking consultation for infertility problems has steadily increased over the past decade, affecting 10%-15% of the sexually active population. Abnormal semen production, a male factor infertility (MFI), is thought to be the cause of up to 50% of all infertilities in developed countries. There are potentially many different causes of male infertility, including hormonal, anatomical, and secondary to exposure to exogenous substances. In many cases of MFI, a definitive cause for abnormalities is never identified. Recently, the research community has given greater attention to identifying causes of MFI ranging from genetic Y chromosome microdeletions to mechanisms of environmental damage on sperm production. Still evolving, is a clear understanding of how many pharmaceutical medications may cause MFI, which is often treatable and reversible. In this review we will outline the data regarding various pharmaceutical medications that have been investigated as possible causes of MFI.
Indexed as
Identifiers
23926519PMC3719368W2161751670What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.