ArticleCancer management and research2013
Cancer-associated thrombosis: clinical presentation and survival.
Article in Cancer management and research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Incidence of thrombosis in patients with hepatocellular carcinoma: systematic review and meta-analysis.Journal of thrombosis and thrombolysis · 2025Pooled it
- Risk factors for postoperative venous thromboembolism in patients with lung cancer: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Trial
- Cancer-associated venous thromboembolism: a comprehensive review.Thrombosis journal · 2025Review
- Venous Thromboembolism in Peritoneal Mesothelioma: Uncovering the Hidden Risk.Annals of surgical oncology · 2024Article
- Thromboembolic Events Burden in Patients With Solid Tumors and Their Predisposing Factors.Cureus · 2022Article
- Survival of patients with cancer associated thrombosis at the Uganda Cancer Institute.Ecancermedicalscience · 2021Review
- Article
- Review
- Tumor-Derived Exosomes Induce the Formation of Neutrophil Extracellular Traps: Implications For The Establishment of Cancer-Associated Thrombosis.Scientific reports · 2017Article
- Epidemiology of venous thromboembolism in the Framingham Heart Study.Thrombosis research · 2016Article
- Observational
- Thrombin-activatable fibrinolysis inhibitor Thr325Ile polymorphism and plasma level in breast cancer: A pilot study.Meta gene · 2015Article
- Co-occurrence of multiple cerebral infarctions due to hypercoagulability associated with malignancy and meningeal carcinomatosis as the initial manifestation of gastric cancer.BMC neurology · 2014Article
- Small but mighty: microparticles as mediators of tumor progression.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2014Article
- Combined pulmonary venous thromboembolism and renal artery thrombosis in a patient with non-small cell lung cancer.Clinical kidney journal · 2014Article
- Simultaneous thrombosis of superior mesenteric artery and superior mesenteric vein following chemotherapy: MDCT findings.Japanese journal of radiology · 2014Article
- Multiple neoplasms, single primaries, and patient survival.Cancer management and research · 2014Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThromboembolic events are important causes of morbidity and mortality in cancer patients. Clinical presentation in a community-based setting has not been fully clarified. The purpose of this study was to evaluate the incidence, risk factors, role of thrombophilia, and subsequent survival following thrombosis in cancer patients.
methodsA retrospective review was undertaken of clinical data for all consecutive patients with histologically confirmed cancer seen by the author at a regional cancer center, with emphasis on cancer-related thrombosis.
resultsBetween 2005 and 2012, of 1874 cancer patients, 307 (16.4%) developed thrombosis during their lifetime. Of these patients, 37 (2%) had a history of thrombosis, while the remaining 270 (14.4%) patients developed thrombosis 3 months before or any time after diagnosis of cancer, which was considered to be cancer-related. These patients included 230 (12.3%) with venous thrombosis, 28 (1.5%) cases with arterial occlusion, and 12 (0.6%) with combined venous and arterial thrombosis. Patients of Caucasian ancestry were more prone to develop thrombosis, with a higher frequency of multiple genetic thrombophilia compared with other ethnic groups. In regression analysis, only advanced stages of cancer and the presence of atherosclerosis were predictive of thrombosis. There were no significant differences between venous and arterial thrombosis. The worst survival was noted in patients who developed thrombosis 3 months prior to or shortly after their diagnosis of cancer. There has been a recent improved survival outcome following therapy.
conclusionIn addition to venous thrombosis, arterial occlusion with stroke and anginal symptoms is relatively common among cancer patients, especially those of Caucasian ancestry, and is possibly related to genetic predisposition.
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