ReviewOpen biology2013
Coordinating cell polarity and cell cycle progression: what can we learn from flies and worms?
Review in Open biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 50 citations in OpenAlex.
- Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues.Science advances · 2026Article
- Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues.bioRxiv : the preprint server for biology · 2025Article
- A CDK1 phosphorylation site oneLife · 2024Article
- Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy.Cancer discovery · 2024Article
- Temporally distinct roles of Aurora A in polarization of the C. elegans zygote.Development (Cambridge, England) · 2024Article
- Article
- Dissecting the Multiple Functions of the Polo-Like Kinase 1 in the C. elegans Zygote.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Temporally distinct roles of Aurora A in polarization of thebioRxiv : the preprint server for biology · 2023Article
- Divergence in cell cycle progression is associated with shifted phenology in a multivoltine moth: the European corn borer, Ostrinia nubilalis.The Journal of experimental biology · 2023Article
- Protein polarization: Spatiotemporal precisions in cell division and differentiation.Current opinion in plant biology · 2022Review
- Cell cycle expression of polarity genes features Rb targeting of Vang.Cells & development · 2022Article
- Review
- Efavirenz induces DNA damage response pathway in lung cancer.Oncotarget · 2020Article
- Coordinating Proliferation, Polarity, and Cell Fate in theFrontiers in cell and developmental biology · 2020Review
- PLK-1 Regulation of Asymmetric Cell Division in the EarlyFrontiers in cell and developmental biology · 2020Review
- Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Caffeic Acid Phenethyl Ester InducesInternational journal of molecular sciences · 2018Article
- A genetic variant in SLC30A2 causes breast dysfunction during lactation by inducing ER stress, oxidative stress and epithelial barrier defects.Scientific reports · 2018Article
- Long non-coding RNAs: crucial regulators of gastrointestinal cancer cell proliferation.Cell death discovery · 2018Review
- Epithelial integrity and cell division: Concerted cell cycle control.Cell cycle (Georgetown, Tex.) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spatio-temporal coordination of events during cell division is crucial for animal development. In recent years, emerging data have strengthened the notion that tight coupling of cell cycle progression and cell polarity in dividing cells is crucial for asymmetric cell division and ultimately for metazoan development. Although it is acknowledged that such coupling exists, the molecular mechanisms linking the cell cycle and cell polarity machineries are still under investigation. Key cell cycle regulators control cell polarity, and thus influence cell fate determination and/or differentiation, whereas some factors involved in cell polarity regulate cell cycle timing and proliferation potential. The scope of this review is to discuss the data linking cell polarity and cell cycle progression, and the importance of such coupling for asymmetric cell division. Because studies in model organisms such as Caenorhabditis elegans and Drosophila melanogaster have started to reveal the molecular mechanisms of this coordination, we will concentrate on these two systems. We review examples of molecular mechanisms suggesting a coupling between cell polarity and cell cycle progression.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.