ArticleAIDS (London, England)2013
Higher rates of AIDS during the first year of antiretroviral therapy among migrants: the importance of tuberculosis.
Article in AIDS (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Low Cholesterol Associated With TB in People Living With HIV in an Asia-Pacific Cohort.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- HIV infection and engagement in the care continuum among migrants and refugees from Venezuela in Colombia: a cross-sectional, biobehavioural survey.The lancet. HIV · 2023Article
- HIV Surveillance and Research for Migrant Populations: Protocol Integrating Respondent-Driven Sampling, Case Finding, and Medicolegal Services for Venezuelans Living in Colombia.JMIR research protocols · 2022Article
- Article
- Foreign-born status as a predictor of engagement in HIV care in a large US metropolitan health system.AIDS care · 2017Article
- Pre-cART Elevation of CRP and CD4+ T-Cell Immune Activation Associated With HIV Clinical Progression in a Multinational Case-Cohort Study.Journal of acquired immune deficiency syndromes (1999) · 2015Article
- Early initiation of antiretroviral treatment: Challenges in the Middle East and North Africa.World journal of virology · 2015Review
- Cohort profile: Antiretroviral Therapy Cohort Collaboration (ART-CC).International journal of epidemiology · 2014Article
- Coming home to die? The association between migration and mortality in rural Tanzania before and after ART scale-up.Global health action · 2014Article
Corrections and comments
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Authors and funding
20 authors at 1 institution in 2 countries.
Funding
Abstract
objectiveIn lower-income countries rates of AIDS-defining events (ADEs) and death are high during the first year of combination antiretroviral therapy (ART). We investigated differences between foreign-born (migrant) and native-born (nonmigrant) patients initiating ART in Europe, the US and Canada, and examined rates of the most common ADEs and mortality during the first year of ART.
designObservational cohort study.
methodsWe studied HIV-positive adults participating in one of 12 cohorts in the Antiretroviral Therapy Cohort Collaboration (ART-CC).
resultsOf 48 854 patients, 25.6% were migrants: 16.1% from sub-Saharan Africa, 5.6% Latin America, 2.3% North Africa/Middle East, and 1.6% Asia. Incidence of ADEs during the first year of ART was 60.8 per 1000 person-years: 69.9 for migrants and 57.7 for nonmigrants [crude hazard ratio (HR) 1.18; 95% confidence interval (CI) 1.08-1.29], adjusted HR (for sex, age, CD4, HIV-1 RNA, ART regimen, prior ADE, probable route of infection and year of initiation, and stratified by cohort) 1.21 (95% CI 1.09-1.34). Rates of tuberculosis were substantially higher in migrants than nonmigrants (14.3 vs. 6.3; adjusted HR 1.94; 95% CI 1.53-2.46). In contrast, mortality was higher among nonmigrants than migrants (crude HR 0.71; 95% CI 0.61-0.84), although excess mortality was partially explained by patient characteristics at start of ART (adjusted HR 0.91; 95% CI 0.76-1.09).
conclusionsDuring the first year of ART, HIV-positive migrants had higher rates of ADEs than nonmigrants. Tuberculosis was the most common ADE among migrants, highlighting the importance of screening for tuberculosis prior to ART initiation in this population.
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