ReviewIndian journal of ophthalmology2013
Ocular allergy and keratoconus.
Review in Indian journal of ophthalmology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- Meta-Analysis of Keratoconus Transcriptomic Data Revealed Altered RNA Editing Levels Impacting Keratin Genomic Clusters.Investigative ophthalmology & visual science · 2023Pooled it
- Sociodemographic and clinical characteristics of keratoconus: multi-centric study from India.Eye (London, England) · 2026Article
- Uncovering pleiotropic loci linking keratoconus and allergic diseases through integrative genomic analyses.Scientific reports · 2026Article
- Tomographic and biomechanical refractive findings in ocular pediatric allergy.Japanese journal of ophthalmology · 2026Article
- Greater exposure to PMScientific reports · 2025Article
- The Effects of Eye Rubbing on Corneal Topography and Biomechanics in Children With Allergic Conjunctivitis.Translational vision science & technology · 2025Observational
- Genetics of Keratoconus: A Comprehensive Review.Genes · 2025Review
- Article
- Subclinical corneal inflammation and subbasal nerve alterations in keratoconus detected by in vivo confocal microscopy: a cross-sectional study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Subclinical ocular surface changes in children with newly diagnosed allergy.Frontiers in pediatrics · 2025Article
- Development and validation of a health practitioner survey on ocular allergy.Scientific reports · 2024Article
- Prevalence and risk factors of Vernal Keratoconjunctivitis among a Ghanaian clinical cohort: A case-control study.Health science reports · 2024Article
- Increased inflammatory mediators in the ocular surface tissue in keratoconus.Molecular vision · 2024Article
- The Level of Awareness of Keratoconus Among the General Population in Hail Region, Saudi Arabia.Cureus · 2023Article
- Prevalence and clinical profile of keratoconus in patients presenting at a provincial hospital in KwaZulu, Natal, South Africa: A case study.Journal of public health in Africa · 2023Article
- Determination of efficacy of repeated CXL and probable risk factors in patients with progressive keratoconus.International ophthalmology · 2023Article
- Inflammatory profile of keratoconic corneal epithelium.BMC ophthalmology · 2023Observational
- Awareness of Keratoconus and Its Association With Eye Rubbing Among the Population in Aseer Province.Cureus · 2023Article
- Systemic Associations with Keratoconus.Life (Basel, Switzerland) · 2023Review
- Diagnosis and management of keratoconus by eye care practitioners in Kenya.BMC ophthalmology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Keratoconus is the most common corneal ectatic disorder, the cause of which is largely unknown. Many factors have been implicated, and the ocular allergy is being one of them. The commonly proposed pathogenesis includes the release of inflammatory mediators due to eye rubbing which may alter the corneal collagen and lead to corneal ectasias. The onset of keratoconus is often early in cases associated with allergy and routine corneal topography may detect subtle forms of keratoconus. These cases may require early keratoplasty and are at an increased risk of having acute corneal hydrops. Surgical outcomes are similar to primary keratoconus cases. However, post-operative epithelial breakdown may be a problem in these cases. Control of allergy and eye rubbing is the best measure to prevent corneal ectasias in cases of ocular allergy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.