ArticleScientific reports2013
Aetiologies of central nervous system infections in adults in Kathmandu, Nepal: a prospective hospital-based study.
Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Investigation of acute encephalitis syndrome with implementation of metagenomic next generation sequencing in Nepal.BMC infectious diseases · 2024Article
- Epidemiological and clinical characteristics of central nervous system infections in a tertiary center: A retrospective study.Health science reports · 2023Article
- Spectrum of central nervous system infections in a tertiary health care centre in Cameroon.The Egyptian journal of neurology, psychiatry and neurosurgery · 2022Article
- A clinical, aetiological, and public health perspective on central nervous system infections in Bolivia, 2017-2018.Scientific reports · 2021Article
- Characteristics and biomarkers of patients with central nervous system infection admitted to a referral hospital in Northern Vietnam.Tropical medicine and health · 2021Article
- Detection ofInfectious disease reports · 2021Article
- Isolation and identification ofAccess microbiology · 2020Article
- Etiology of Central Nervous System Infections in a Rural Area of Nepal Using Molecular Approaches.The American journal of tropical medicine and hygiene · 2019Article
- Increased serum vascular endothelial growth factor is associated with acute viral encephalitis in Bangladeshi children.Scientific reports · 2017Article
- Dengue virus and Japanese encephalitis virus infection of the central nervous system share similar profiles of cytokine accumulation in cerebrospinal fluid.Central-European journal of immunology · 2017Article
- Tuberculous meningitis is a major cause of mortality and morbidity in adults with central nervous system infections in Kota Kinabalu, Sabah, Malaysia: an observational study.BMC infectious diseases · 2016Observational
- Herpes simplex virus encephalitis in Peru: a multicentre prospective study.Epidemiology and infection · 2016Article
- Establishment of an Algorithm Using prM/E- and NS1-Specific IgM Antibody-Capture Enzyme-Linked Immunosorbent Assays in Diagnosis of Japanese Encephalitis Virus and West Nile Virus Infections in Humans.Journal of clinical microbiology · 2016Article
- GeneXpert MTB/RIF assay as initial test for diagnosis of tuberculous meningitis.BMJ case reports · 2015Article
- Viral aetiology of central nervous system infections in adults admitted to a tertiary referral hospital in southern Vietnam over 12 years.PLoS neglected tropical diseases · 2014Article
- Limited geographic distribution of the novel cyclovirus CyCV-VN.Scientific reports · 2014Article
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16 authors.
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Abstract
We conducted a prospective hospital based study from February 2009-April 2011 to identify the possible pathogens of central nervous system (CNS) infections in adults admitted to a tertiary referral hospital (Patan Hospital) in Kathmandu, Nepal. The pathogens of CNS infections were confirmed in cerebrospinal fluid (CSF) using molecular diagnostics, culture (bacteria) and serology. 87 patients were recruited for the study and the etiological diagnosis was established in 38% (n = 33). The bacterial pathogens identified were Neisseria meningitidis (n = 6); Streptococcus pneumoniae (n = 5) and Staphylococcus aureus (n = 2) in 13/87(14%). Enteroviruses were found in 12/87 (13%); Herpes Simplex virus (HSV) in 2/87(2%). IgM against Japanese encephalitis virus (JEV) was detected in the CSF of 11/73 (15%) tested samples. This is the first prospective molecular and serology based CSF analysis in adults with CNS infections in Kathmandu, Nepal. JEV and enteroviruses were the most commonly detected pathogens in this setting.
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