ArticleAging2013
Vitamin D deficiency is a risk factor for obesity and diabetes type 2 in women at late reproductive age.
Article in Aging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Vitamin D Deficiency Is Inversely Associated with Homeostatic Model Assessment of Insulin Resistance.Nutrients · 2021Pooled it
- Insulin Resistance Is Inversely Associated with the Status of Vitamin D in Both Diabetic and Non-Diabetic Populations.Nutrients · 2021Pooled it
- Investigating the Association Between Serum 25-Hydroxyvitamin D (25(OH)D) and Body Mass Index (BMI) With In Vitro Fertilization (IVF) Outcomes Among Iranian Women: A Case-Control Study.Health science reports · 2026Article
- Vitamin D Deficiency, Obesity, and Metabolic Parameters in Chilean Older Adults.Journal of personalized medicine · 2026Article
- Can Myokines Serve as Supporters of Muscle-Brain Connectivity in Obesity and Type 2 Diabetes? Potential of Exercise and Nutrition Interventions.Nutrients · 2025Review
- Relationship between Serum 25-Hydroxyvitamin D Levels and Hormonal Status in Infertile Women: A Retrospective Study.Diagnostics (Basel, Switzerland) · 2023Article
- Diabetes and skin cancers: Risk factors, molecular mechanisms and impact on prognosis.World journal of clinical cases · 2022Review
- Article
- [Vitamin D deficiency in Russia: the first results of a registered, non-interventional study of the frequency of vitamin D deficiency and insufficiency in various geographic regions of the country].Problemy endokrinologii · 2021Article
- Article
- The Moderate Correlation Between 25(OH)D Serum and Saliva in Healthy People with Low Vitamin D Intake.International journal of general medicine · 2021Article
- Evaluation of the Effect of Vitamin D Supplementation on Anthropometric Indicators and Dietary Intake of Patients with Type 2 Diabetes.Reports of biochemistry & molecular biology · 2021Article
- Knowledge, Attitude and Practice about Vitamin D among Pregnant Women at a Municipality of Bhaktapur.JNMA; journal of the Nepal Medical Association · 2020Article
- Diet Quality and Total Daily Price of Foods Consumed among Iranian Diabetic Patients.International journal of preventive medicine · 2019Article
- The Relationship between Vitamin D Status and the Menstrual Cycle in Young Women: A Preliminary Study.Nutrients · 2018Article
- The State of Knowledge about Nutrition Sources of Vitamin D, Its Role in the Human Body, and Necessity of Supplementation among Parents in Central Poland.International journal of environmental research and public health · 2018Article
- Lower vitamin D levels in Saudi pregnant women are associated with higher risk of developing GDM.BMC pregnancy and childbirth · 2018Article
- Is There Any Relationship between Plasma 25-Hydroxyvitamin D₃, Adipokine Profiles and Excessive Body Weight in Type 2 Diabetic Patients?International journal of environmental research and public health · 2017Article
- Vitamin D levels in subjects with or without chronic kidney disease among Veterans with diabetes in North East United States.World journal of diabetes · 2017Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It was suggested that glucose metabolism and body fat content depend on serum levels of 25-hydroxyvitamin D [25(OH)D]. We studied 320 healthy women at late reproductive age of 40 to 52 years old (mean age 46.1±4.5) from St. Petersburg (North-West region of Russia). 25(ОН)D levels were from 19.4 to 134.0 nMol/L (mean 52.9±22.7). Vitamin D deficiency (lower than 50 nMol/L) and insufficiency (50-75 nMol/L) was revealed in 59.1% and 27.8% of women, respectively. The study showed that low 25(OH)D levels were associated with obesity (r=-0.35, p$#X003C0.01), increased plasma glucose levels after OGTT (r=-0.31, p$#X003C0.01) and decreased insulin sensitivity index (r=-0.28, p$#X003C0.01). We found that 25(OH)D levels below 50 nMol/L were associated with obesity risk (OR 2.25[1.05-3.95], CI 95%) but not with risk of impaired glucose metabolism (1.07[0.54-2.12],CI95%). Our results showed that vitamin D insufficiency is highly prevalent in the population of healthy women. Low 25(OH)D levels correlated with high body fat, glucose levels and decreased insulin sensitivity. We conclude that vitamin D deficiency is a potential risk factor for obesity and development of insulin resistance leading to diabetes type 2.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.