ArticlePloS one2013
Reorganization of the intact somatosensory cortex immediately after spinal cord injury.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- Cortical layer-specific modulation of neuronal activity after sensory deprivation due to spinal cord injury.The Journal of physiology · 2021Article
- Hindlimb Somatosensory Information Influences Trunk Sensory and Motor Cortices to Support Trunk Stabilization.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Observations of Autonomic Variability Following Central Neuromodulation for Chronic Neuropathic Pain in Spinal Cord Injury.Neuromodulation : journal of the International Neuromodulation Society · 2021Article
- Myelination of Callosal Axons Is Hampered by Early and Late Forelimb Amputation in Rats.Cerebral cortex communications · 2021Article
- Sensory Circuit Remodeling and Movement Recovery After Spinal Cord Injury.Frontiers in neuroscience · 2021Review
- Dementia, Depression, and Associated Brain Inflammatory Mechanisms after Spinal Cord Injury.Cells · 2020Review
- Sensorimotor plasticity after spinal cord injury: a longitudinal and translational study.Annals of clinical and translational neurology · 2019Observational
- Multimodal Evaluation of TMS - Induced Somatosensory Plasticity and Behavioral Recovery in Rats With Contusion Spinal Cord Injury.Frontiers in neuroscience · 2019Article
- Cortical Reorganization of Sensorimotor Systems and the Role of Intracortical Circuits After Spinal Cord Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2018Review
- Why Does the Cortex Reorganize after Sensory Loss?Trends in cognitive sciences · 2018Review
- Supraspinal respiratory plasticity following acute cervical spinal cord injury.Experimental neurology · 2017Article
- Interactive Effects Between Exercise and Serotonergic Pharmacotherapy on Cortical Reorganization After Spinal Cord Injury.Neurorehabilitation and neural repair · 2016Article
- HAL® exoskeleton training improves walking parameters and normalizes cortical excitability in primary somatosensory cortex in spinal cord injury patients.Journal of neuroengineering and rehabilitation · 2015Article
- Remodeling the Dendritic Spines in the Hindlimb Representation of the Sensory Cortex after Spinal Cord Hemisection in Mice.PloS one · 2015Article
- Cortical reorganization after spinal cord injury: always for good?Neuroscience · 2014Review
- Increased cortical responses to forepaw stimuli immediately after peripheral deafferentation of hindpaw inputs.Scientific reports · 2014Article
- The reactivation of somatosensory cortex and behavioral recovery after sensory loss in mature primates.Frontiers in systems neuroscience · 2014Review
- Spinal cord transection-induced allodynia in rats--behavioral, physiopathological and pharmacological characterization.PloS one · 2014Article
- Rubber hand illusion induced by touching the face ipsilaterally to a deprived hand: evidence for plastic "somatotopic" remapping in tetraplegics.Frontiers in human neuroscience · 2014Article
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Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sensory deafferentation produces extensive reorganization of the corresponding deafferented cortex. Little is known, however, about the role of the adjacent intact cortex in this reorganization. Here we show that a complete thoracic transection of the spinal cord immediately increases the responses of the intact forepaw cortex to forepaw stimuli (above the level of the lesion) in anesthetized rats. These increased forepaw responses were independent of the global changes in cortical state induced by the spinal cord transection described in our previous work (Aguilar et al., J Neurosci 2010), as the responses increased both when the cortex was in a silent state (down-state) or in an active state (up-state). The increased responses in the intact forepaw cortex correlated with increased responses in the deafferented hindpaw cortex, suggesting that they could represent different points of view of the same immediate state-independent functional reorganization of the primary somatosensory cortex after spinal cord injury. Collectively, the results of the present study and of our previous study suggest that both state-dependent and state-independent mechanisms can jointly contribute to cortical reorganization immediately after spinal cord injury.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.