ArticlePloS one2013
The fusarium mycotoxin deoxynivalenol can inhibit plant apoptosis-like programmed cell death.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 66 citations in OpenAlex.
- Article
- A comparison between the role of enniatins and deoxynivalenol in Fusarium virulence on different tissues of common wheat.BMC plant biology · 2024Article
- Diverse mycotoxin threats to safe food and feed cereals.Essays in biochemistry · 2023Review
- Review
- Image-based time series analysis to establish differential disease progression for twoFrontiers in plant science · 2023Article
- Fungal Secondary Metabolites and Small RNAs Enhance Pathogenicity during Plant-Fungal Pathogen Interactions.Journal of fungi (Basel, Switzerland) · 2022Review
- Article
- Mycotoxins' Toxicological Mechanisms Involving Humans, Livestock and Their Associated Health Concerns: A Review.Toxins · 2022Review
- Genetic dissection of a pericentromeric region of barley chromosome 6H associated with Fusarium head blight resistance, grain protein content and agronomic traits.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Arabidopsis P4 ATPase-mediated cell detoxification confers resistance to Fusarium graminearum and Verticillium dahliae.Nature communications · 2021Article
- Article
- Apoptosis is not conserved in plants as revealed by critical examination of a model for plant apoptosis-like cell death.BMC biology · 2021Article
- Contrasting transcriptional responses to Fusarium virguliforme colonization in symptomatic and asymptomatic hosts.The Plant cell · 2021Article
- Multi-Mycotoxin Contamination of Maize Silages in Flanders, Belgium: Monitoring Mycotoxin Levels from Seed to Feed.Toxins · 2021Article
- Effectors of Plant Necrotrophic Fungi.Frontiers in plant science · 2021Review
- Hydrogen sulfide negatively regulates cd-induced cell death in cucumber (Cucumis sativus L) root tip cells.BMC plant biology · 2020Article
- Infection cushions of Fusarium graminearum are fungal arsenals for wheat infection.Molecular plant pathology · 2020Article
- Searching for FHB Resistances in Bread Wheat: Susceptibility at the Crossroad.Frontiers in plant science · 2020Review
- Mycotoxins in Conversation With Bacteria and Fungi.Frontiers in microbiology · 2019Review
- Impact of Fungi Co-occurrence on Mycotoxin Contamination in Maize During the Growing Season.Frontiers in microbiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Fusarium genus of fungi is responsible for commercially devastating crop diseases and the contamination of cereals with harmful mycotoxins. Fusarium mycotoxins aid infection, establishment, and spread of the fungus within the host plant. We investigated the effects of the Fusarium mycotoxin deoxynivalenol (DON) on the viability of Arabidopsis cells. Although it is known to trigger apoptosis in animal cells, DON treatment at low concentrations surprisingly did not kill these cells. On the contrary, we found that DON inhibited apoptosis-like programmed cell death (PCD) in Arabidopsis cells subjected to abiotic stress treatment in a manner independent of mitochondrial cytochrome c release. This suggested that Fusarium may utilise mycotoxins to suppress plant apoptosis-like PCD. To test this, we infected Arabidopsis cells with a wild type and a DON-minus mutant strain of F. graminearum and found that only the DON producing strain could inhibit death induced by heat treatment. These results indicate that mycotoxins may be capable of disarming plant apoptosis-like PCD and thereby suggest a novel way that some fungi can influence plant cell fate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.