ArticleThe Plant cell2013
WRKY6 transcription factor restricts arsenate uptake and transposon activation in Arabidopsis.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
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Who cites it
77 citing papers in PubMed.
- Sulfur in dialogue with phosphorus, nitrogen, and iron: regulatory networks in plant nutrient homeostasis.Journal of experimental botany · 2026Review
- Phosphate Transporters Mediate the Uptake of Monothioarsenate.Plant, cell & environment · 2026Article
- Knocking out OsPht1;9-1;10 genes decreases arsenic accumulation in rice (Oryza sativa) grains.Communications biology · 2026Article
- Genome-wide characterization of WRKYs and identification of SpWRKY40 and SpWRKY51 as transcription activators in Sesuvium portulacastrum.Functional & integrative genomics · 2025Article
- Comprehensive review of multiomics applications and remediation of plant heavy metal toxicity.Stress biology · 2025Review
- Zinc Oxide Nanoparticle-Mediated Root Metabolic Reprogramming for Arsenic Tolerance in Soybean.Plants (Basel, Switzerland) · 2024Article
- Leveraging multi-omics tools to comprehend responses and tolerance mechanisms of heavy metals in crop plants.Functional & integrative genomics · 2024Review
- WRKY Transcription Factors in Response to Metal Stress in Plants: A Review.International journal of molecular sciences · 2024Review
- Recent advances in research on phosphate starvation signaling in plants.Journal of plant research · 2024Review
- Review
- The Molecular Mechanism of the Response of Rice to Arsenic Stress and Effective Strategies to Reduce the Accumulation of Arsenic in Grain.International journal of molecular sciences · 2024Review
- Genetics and metabolic responses of Artemisia annua L to the lake of phosphorus under the sparingly soluble phosphorus fertilizer: evidence from transcriptomics analysis.Functional & integrative genomics · 2024Article
- Plants' molecular behavior to heavy metals: from criticality to toxicity.Frontiers in plant science · 2024Review
- Transcriptome analysis ofFrontiers in microbiology · 2024Article
- Review
- Effect of phosphate on arsenic species uptake in plants under hydroponic conditions.Journal of plant research · 2023Article
- Microbial biochemical pathways of arsenic biotransformation and their application for bioremediation.Folia microbiologica · 2023Review
- Article
- Plasma membrane-associated calcium signaling regulates arsenate tolerance in Arabidopsis.Plant physiology · 2023Article
- RNA sequencing in Artemisia annua L explored the genetic and metabolic responses to hardly soluble aluminum phosphate treatment.Functional & integrative genomics · 2023Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stress constantly challenges plant adaptation to the environment. Of all stress types, arsenic was a major threat during the early evolution of plants. The most prevalent chemical form of arsenic is arsenate, whose similarity to phosphate renders it easily incorporated into cells via the phosphate transporters. Here, we found that arsenate stress provokes a notable transposon burst in plants, in coordination with arsenate/phosphate transporter repression, which immediately restricts arsenate uptake. This repression was accompanied by delocalization of the phosphate transporter from the plasma membrane. When arsenate was removed, the system rapidly restored transcriptional expression and membrane localization of the transporter. We identify WRKY6 as an arsenate-responsive transcription factor that mediates arsenate/phosphate transporter gene expression and restricts arsenate-induced transposon activation. Plants therefore have a dual WRKY-dependent signaling mechanism that modulates arsenate uptake and transposon expression, providing a coordinated strategy for arsenate tolerance and transposon gene silencing.
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