Trial reportEuropean journal of nutrition2014
Dietary fat differentially influences the lipids storage on the adipose tissue in metabolic syndrome patients.
Trial report in European journal of nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02189200 (Effect of Nutritional Counseling Associated With the Ingestion of Oat Bran in Hypercholesterolemic Subjects in Secondary Prevention), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Nutritional Counseling Associated With the Ingestion of Oat Bran in Hypercholesterolemic Subjects in Secondary Prevention
Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Serum FABP4 concentrations decrease after Roux-en-Y gastric bypass but not after intensive medical management.Surgery · 2019Trial
- Dietary fat may modulate adipose tissue homeostasis through the processes of autophagy and apoptosis.European journal of nutrition · 2017Trial
- Untargeted Metabolomics and Gut Microbiota Modulation Study of Fermented Brown Rice for Obesity.ACS omega · 2024Article
- Article
- Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial.Nutrients · 2018Article
- An Overview of Novel Dietary Supplements and Food Ingredients in Patients with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease.Molecules (Basel, Switzerland) · 2018Review
- Nutrition, insulin resistance and dysfunctional adipose tissue determine the different components of metabolic syndrome.World journal of diabetes · 2016Review
- The Effect of Marine Derived n-3 Fatty Acids on Adipose Tissue Metabolism and Function.Journal of clinical medicine · 2015Review
- Glycerol Production from Glucose and Fructose by 3T3-L1 Cells: A Mechanism of Adipocyte Defense from Excess Substrate.PloS one · 2015Article
- Psychological Experiences of Adolescent Girls with Polycystic Ovary Syndrome: A Qualitative Study.Iranian journal of nursing and midwifery researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAdipose tissue is now recognized as a highly active metabolic and endocrine organ. Our aim was to investigate the effect of the dietary fat on the two main adipose tissue functions, endocrine and lipid store, by analyzing the adipose tissue gene expression from metabolic syndrome patients.
methodsA randomized, controlled trial conducted within the LIPGENE study assigned 39 metabolic syndrome patients to 1 of 4 isoenergetic diets: (1) high-saturated fatty acid (HSFA), (2) high-monounsaturated fatty acid (HMUFA), (3) low-fat, high-complex carbohydrate diet supplemented with long-chain n-3 fatty acids (LFHCC n-3), and (4) low-fat, high-complex carbohydrate diet supplemented with placebo (LFHCC), for 12 weeks each. A fat challenge reflecting the fatty acid composition as the original diets was conducted post-intervention.
resultsThe long-term consumption of HSFA, LFHCC, and LFHCC n-3 diets, but not HMUFA diet, decreased the perilipin fasting mRNA levels. LFHCC diet consumption increased fasting FABP4 expression, while it was reduced by the consumption of LFHCC n-3 diet. LFHCC meal reduced, while LFHCC n-3 meal intake increased postprandial CAV1 expression.
conclusionThe quantity and quality of dietary fat induce differential lipid storage and processing related gene expression, which may interact with the expression of adipokines through common regulatory mechanisms.
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Registered trials
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