Evidence map›Paper›PMID 23922006›Full record

ReviewPharmacogenetics and genomics2013

PharmGKB summary: cyclosporine and tacrolimus pathways.

Julia M Barbarino, Christine E Staatz, Raman Venkataramanan, Teri E Klein, Russ B Altman

Abstract readReview
In one paragraph

Review in Pharmacogenetics and genomics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Guideline
  2. Polymorphisms inFrontiers in pharmacology · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia M BarbarinoDepartments of aGenetics bBioengineering, Stanford University, Stanford, California cDepartment of Pharmaceutical Sciences, School of Pharmacy dDepartment of Pathology, School of Medicine, Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA eSchool of Pharmacy, University of Queensland, Brisbane, Australia.
Christine E Staatz
Raman Venkataramanan
Teri E Klein
Russ B Altman

Funding

PharmGKB: pharmacogenomics knowledge for precision medicineR24GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, KLEIN, TERI ELLEN · 2010 to 2018
$25.2M
NIGMS NIH HHS R24 GM061374NIGMS NIH HHS R24 GM61374
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CyclosporineImmunosuppressive AgentsTacrolimusATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily B, Member 1CalcineurinCytochrome P-450 CYP3AGenetic VariationGraft RejectionHumansMAP Kinase Signaling SystemOrgan TransplantationPharmacogeneticsPolymorphism, GeneticTransforming Growth Factor beta1ABCB1 protein, humanATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily B, Member 1CalcineurinCyclosporineCYP3A4 protein, humanCYP3A5 protein, humanCytochrome P-450 CYP3AImmunosuppressive AgentsTacrolimusTGFB1 protein, humanTransforming Growth Factor beta1

Identifiers

PMID23922006
PMCPMC4119065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.