Evidence map›Paper›PMID 23921975›Full record

ArticleIntensive care medicine2013

Lack of association between body weight and mortality in patients on veno-venous extracorporeal membrane oxygenation.

Suhel Al-Soufi, Hergen Buscher, Nguyen Dinh Nguyen, Peter Rycus, Priya Nair

Abstract read
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Article in Intensive care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
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  5. Article
  6. Article
  7. Article
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  9. Article
  10. Review
  11. Article
  12. How to ventilate obese patients in the ICU.Intensive care medicine · 2020
    Review
  13. Article
  14. [Extreme obesity-particular aspect of invasive and noninvasive ventilation].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2019
    Review
  15. The use of VV-ECMO in patients with drug dependencies.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2018
    Article
  16. Article
  17. Article
  18. Article
  19. Body mass index and echocardiography in refractory ARDS treated with veno-venous extracorporeal membrane oxygenation.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Suhel Al-SoufiIntensive Care Unit, St Vincent's Hospital, Victoria Street Darlinghurst, Sydney, NSW, 2010, Australia, suhelsoufi@gmx.de.
Hergen Buscher
Nguyen Dinh Nguyen
Peter Rycus
Priya Nair

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyse the association of body weight with hospital mortality of adult patients supported with veno-venous extracorporeal membrane oxygenation (VV ECMO).

methodsRetrospective analysis of the international Extracorporeal Life Support Organization (ELSO) registry. Univariate and multivariable logistic regression analyses were used to estimate the odds ratio (OR) of hospital death for each body weight quartile. Adjustment was made for demographic, physiologic and ECMO-related characteristics. We undertook a similar analysis for the subgroup of patients with confirmed H1N1 infection on VV ECMO.

resultsThe study group consisted of 1,334 adult patients supported with VV ECMO between 2005 and 2011 with a median (Q1, Q3) body weight of 80 kg (69, 101 kg). Univariate analysis identified increased body weight to be associated with a reduced risk of death. In multivariable analysis, only age greater than 53 years, primary diagnosis other than pneumonia and intubation time longer than 3 days prior to initiation of ECMO were independent risk factors for mortality, whereas the association between high body weight and adjusted risk of death (OR 0.73, 95% CI 0.52-1.04, P = 0.08) was no longer statistically significant. The body weight of the 196 patients with confirmed H1N1 infection was significantly higher than that of the remaining study group. Body weight was not significantly associated with risk of death for these patients either (univariate OR for Q4 vs. Q1: 0.75, 95% CI 0.33-1.72, P = 0.49).

conclusionsIncreased body weight was not a risk factor for hospital mortality in adult patients who required support with VV ECMO. High body weight should therefore not be regarded as a contraindication to initiation of VV ECMO in adult patients. Data collection and reporting that include patient height in addition to body weight would facilitate future research into the association of obesity with outcome of ECMO patients.

Indexed as

Body WeightHospital MortalityAdultExtracorporeal Membrane OxygenationFemaleHumansMaleMiddle AgedRegistriesRetrospective StudiesRisk Factors

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.