ArticleMarine drugs2013
Hepatotoxic seafood poisoning (HSP) due to microcystins: a threat from the ocean?
Article in Marine drugs, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 44 citations in OpenAlex.
- The Portuguese man-of-war genome reveals the genetic basis of medusa loss and sea-air interface adaptation.National science review · 2026Article
- Interannual variation in freshwater and marine phycotoxins quantified from oysters cultured across diverse coastal sites.Aquaculture reports · 2026Article
- Biodegradation of Microcystins by Aquatic BacteriaToxins · 2025Article
- New perspectives on picocyanobacteria and understudied cyanobacterial diversity in the Albemarle Pamlico sound system, North Carolina, USA.Frontiers in microbiology · 2025Article
- Co-occurrence of marine and freshwater phycotoxins in oysters, and analysis of possible predictors for management.Toxicon: X · 2023Article
- Bioactive Potential of Two Marine Picocyanobacteria Belonging toMicroorganisms · 2021Article
- The link between pharmaceuticals and cyanobacteria: a review regarding ecotoxicological, ecological, and sanitary aspects.Environmental science and pollution research international · 2021Review
- Salt Shock Responses ofToxins · 2020Article
- Removal of MCs by BiEnvironmental science and pollution research international · 2018Article
- Review
- Multiple Stressors at the Land-Sea Interface: Cyanotoxins at the Land-Sea Interface in the Southern California Bight.Toxins · 2017Article
- Planctomycetes as Novel Source of Bioactive Molecules.Frontiers in microbiology · 2016Article
- Article
- Article
- Article
- Cyanobacteria and cyanotoxins: from impacts on aquatic ecosystems and human health to anticarcinogenic effects.Toxins · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyanobacterial blooms are a major and growing problem for freshwater ecosystems worldwide that increasingly concerns public health, with an average of 60% of blooms known to be toxic. The most studied cyanobacterial toxins belong to a family of cyclic heptapeptide hepatotoxins, called microcystins. The microcystins are stable hydrophilic cyclic heptapeptides with a potential to cause cell damage following cellular uptake via organic anion-transporting proteins (OATP). Their intracellular biologic effects presumably involve inhibition of catalytic subunits of protein phosphatases (PP1 and PP2A) and glutathione depletion. The microcystins produced by cyanobacteria pose a serious problem to human health, if they contaminate drinking water or food. These toxins are collectively responsible for human fatalities, as well as continued and widespread poisoning of wild and domestic animals. Although intoxications of aquatic organisms by microcystins have been widely documented for freshwater ecosystems, such poisonings in marine environments have only occasionally been reported. Moreover, these poisonings have been attributed to freshwater cyanobacterial species invading seas of lower salinity (e.g., the Baltic) or to the discharge of freshwater microcystins into the ocean. However, recent data suggest that microcystins are also being produced in the oceans by a number of cosmopolitan marine species, so that Hepatotoxic Seafood Poisoning (HSP) is increasingly recognized as a major health risk that follows consumption of contaminated seafood.
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Registered trials
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