ArticleThe Journal of biological chemistry2013
Bacterial division proteins FtsZ and ZipA induce vesicle shrinkage and cell membrane invagination.
Article in The Journal of biological chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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Who cites it
39 citing papers in PubMed, 81 citations in OpenAlex.
- Devising a divisome for synthetic cells.Nature reviews. Chemistry · 2026Review
- Optimizing spatial organization of FtsZ rings for large-scale constriction in synthetic cells.Nature communications · 2026Article
- Protein-Protein Interactions as Promising Molecular Targets for Novel Antimicrobials Aimed at Gram-Negative Bacteria.International journal of molecular sciences · 2025Review
- In vitro assembly, positioning and contraction of a division ring in minimal cells.Nature communications · 2022Article
- Towards a synthetic cell cycle.Nature communications · 2021Review
- FtsZ Interactions and Biomolecular Condensates as Potential Targets for New Antibiotics.Antibiotics (Basel, Switzerland) · 2021Review
- FtsZ Reorganization Facilitates Deformation of Giant Vesicles in Microfluidic Traps*.Angewandte Chemie (International ed. in English) · 2020Article
- Transcription and Translation in Cytomimetic Protocells Perform Most Efficiently at Distinct Macromolecular Crowding Conditions.ACS synthetic biology · 2020Article
- Cell-free biogenesis of bacterial division proto-rings that can constrict liposomes.Communications biology · 2020Article
- Engineering bio-mimicking functional vesicles with multiple compartments for quantifying molecular transport.Chemical science · 2020Article
- Nano-encapsulated Escherichia coli Divisome Anchor ZipA, and in Complex with FtsZ.Scientific reports · 2019Article
- Toward long-lasting artificial cells that better mimic natural living cells.Emerging topics in life sciences · 2019Article
- Synthetic cell division via membrane-transforming molecular assemblies.BMC biology · 2019Review
- Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein.Scientific reports · 2019Article
- Gene-Expressing Liposomes as Synthetic Cells for Molecular Communication Studies.Frontiers in bioengineering and biotechnology · 2019Review
- Escherichia coli ZipA Organizes FtsZ Polymers into Dynamic Ring-Like Protofilament Structures.mBio · 2018Article
- On-chip microfluidic production of cell-sized liposomes.Nature protocols · 2018Article
- Nucleotide and receptor density modulate binding of bacterial division FtsZ protein to ZipA containing lipid-coated microbeads.Scientific reports · 2017Article
- On-chip density-based purification of liposomes.Biomicrofluidics · 2017Article
- Preparation of Giant Vesicles Encapsulating Microspheres by Centrifugation of a Water-in-oil Emulsion.Journal of visualized experiments : JoVE · 2017Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Permeable vesicles containing the proto-ring anchoring ZipA protein shrink when FtsZ, the main cell division protein, polymerizes in the presence of GTP. Shrinkage, resembling the constriction of the cytoplasmic membrane, occurs at ZipA densities higher than those found in the cell and is modulated by the dynamics of the FtsZ polymer. In vivo, an excess of ZipA generates multilayered membrane inclusions within the cytoplasm and causes the loss of the membrane function as a permeability barrier. Overproduction of ZipA at levels that block septation is accompanied by the displacement of FtsZ and two additional division proteins, FtsA and FtsN, from potential septation sites to clusters that colocalize with ZipA near the membrane. The results show that elementary constriction events mediated by defined elements involved in cell division can be evidenced both in bacteria and in vesicles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.