Evidence map›Paper›PMID 23920679›Full record

ArticleStudies in health technology and informatics2013

A formal representation for numerical data presented in published clinical trial reports.

Maurine Tong, William Hsu, Ricky K Taira

Abstract read
In one paragraph

Article in Studies in health technology and informatics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maurine TongDepartment of Bioengineering, University of California, Los Angeles.
William Hsu
Ricky K Taira

Funding

Data Structuring and Visualization System for Neuro-oncologyR01LM009961 · NLM · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TAIRA, RICKY K. · 2009 to 2010
$1.7M
NLM NIH HHS R01 LM009961NLM NIH HHS R01-LM009961
6 · The paper itself

Abstract

Assessing the quality of and integrating clinical trial reports are necessary to practice evidence-based medicine. In particular, the numerical data is essential to understanding the strength and quality of the clinical trial study. In this paper, we present a formal representation for standardizing numerical data in published clinical trial reports, and our efforts towards developing computational tools to capture and visualize this representation. The approach includes two aspects: a process model used to precisely define experimental context behind the numerical value; and a spreadsheet, an intuitive and familiar tool used to organize numerical data. We demonstrated this representation using clinical trial reports on non-small cell lung cancer (NSCLC). We performed a preliminary evaluation to determine the usefulness of this formalism for identifying the characteristics, quality and significance of a clinical trial. Our initial results demonstrate that the representation is sufficiently expressive to capture reported numerical information in published papers.

Indexed as

Periodicals as TopicTerminology as TopicVocabulary, ControlledClinical Trials as TopicData MiningDocumentationEvidence-Based MedicineHumansLung NeoplasmsNatural Language ProcessingOutcome Assessment, Health CareSoftwareUser-Computer Interface

Identifiers

PMID23920679
PMCPMC5025869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.