ArticleBiomicrofluidics2012
A hydrodynamic focusing microchannel based on micro-weir shear lift force.
Article in Biomicrofluidics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- An Extensive Study of the Influence of Key Flow Variables on Printed Line Quality Outcomes during Aerosol Jet Printing Using Coupled Three-Dimensional Numerical Models.Materials (Basel, Switzerland) · 2024Article
- Influence of the internal structure of straight microchannels on inertial transport behavior of particles.Heliyon · 2024Article
- Recent Developments in Inertial and Centrifugal Microfluidic Systems along with the Involved Forces for Cancer Cell Separation: A Review.Sensors (Basel, Switzerland) · 2023Review
- Using binary optical elements (BOEs) to generate rectangular spots for illumination in micro flow cytometer.Biomicrofluidics · 2016Article
- Making a hydrophoretic focuser tunable using a diaphragm.Biomicrofluidics · 2014Article
- Hydrodynamic particle focusing design using fluid-particle interaction.Biomicrofluidics · 2013Article
- High-throughput inertial particle focusing in a curved microchannel: Insights into the flow-rate regulation mechanism and process model.Biomicrofluidics · 2013Article
- Optimization of microfluidic microsphere-trap arrays.Biomicrofluidics · 2013Article
- Experimental characterisation of a novel viscoelastic rectifier design.Biomicrofluidics · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel microflow cytometer is proposed in which the particles are focused in the horizontal and vertical directions by means of the Saffman shear lift force generated within a micro-weir microchannel. The proposed device is fabricated on stress-relieved glass substrates and is characterized both numerically and experimentally using fluorescent particles with diameters of 5 μm and 10 μm, respectively. The numerical results show that the micro-weir structures confine the particle stream to the center of the microchannel without the need for a shear flow. Moreover, the experimental results show that the particles emerging from the micro-weir microchannel pass through the detection region in a one-by-one fashion. The focusing effect of the micro-weir microchannel is quantified by computing the normalized variance of the optical detection signal intensity. It is shown that the focusing performance of the micro-weir structure is equal to 99.76% and 99.57% for the 5-μm and 10-μm beads, respectively. Overall, the results presented in this study confirm that the proposed microcytometer enables the reliable sorting and counting of particles with different diameters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.