ArticlePediatrics2013
Outcomes of children with severe bronchopulmonary dysplasia who were ventilator dependent at home.
Article in Pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03961139 (Continuous Versus Intermittent Bolus Feeding in Very Preterm Infants - Effects on Respiratory Morbidity), which is not on this map. Cited by 66 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Continuous Versus Intermittent Bolus Feeding in Very Preterm Infants - Effects on Respiratory Morbidity: A Multicentre Randomised Controlled Clinical Trial
Who cites it
66 citing papers in PubMed, 3 syntheses or guidelines pooled it, 176 citations in OpenAlex.
- Readmission and mortality among children requiring long-term mechanical ventilation via tracheostomy: a systematic review.BMC pulmonary medicine · 2025Pooled it
- Liberation and mortality outcomes in pediatric long-term ventilation: A qualitative systematic review.Pediatric pulmonology · 2020Pooled it
- An Official American Thoracic Society Clinical Practice Guideline: Pediatric Chronic Home Invasive Ventilation.American journal of respiratory and critical care medicine · 2016Guideline
- Creation & implementation of discharge guidelines for preterm infants with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Clinical outcomes of paediatric home ventilation in South Korea: liberation and mortality.BMJ open respiratory research · 2026Article
- Home Non-Invasive Ventilation as an Alternative to Tracheostomy in Infants With Moderate-to-Severe Bronchopulmonary Dysplasia: A Retrospective Cohort Study.Pediatric pulmonology · 2026Article
- Factors associated with liberation from home mechanical ventilation and tracheostomy decannulation in infants and children with severe bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Quantifying Antibiotic Prescribing in Children With Tracheostomies.Pediatric pulmonology · 2025Article
- Outcomes of extremely preterm infants with bronchopulmonary dysplasia: a retrospective cohort study.Scientific reports · 2025Article
- Time Toxicity: Quantifying Healthcare Utilization Attributable to Pediatric Home Ventilation.Pediatric pulmonology · 2025Article
- [Liberation of mechanical ventilation in tracheostomized pediatric patients during their stay in the intensive care unit]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025Article
- Care Utilization for Acute Respiratory Infections in Children Requiring Invasive Long-Term Mechanical Ventilation.Pediatric pulmonology · 2025Article
- Outcomes of infants and children with bronchopulmonary dysplasia-associated pulmonary hypertension who required home ventilation.Pediatric research · 2025Article
- Small Extracellular Vesicles Derived from Cord Blood Plasma and Placental Mesenchymal Stem Cells Attenuate Acute Lung Injury Induced by Lipopolysaccharide (LPS).International journal of molecular sciences · 2024Article
- An algorithm for discontinuing mechanical ventilation in boys with x-linked myotubular myopathy after positive response to gene therapy: the ASPIRO experience.Respiratory research · 2024Article
- Effect of Speaking Valves on Tracheostomy Decannulation.International archives of otorhinolaryngology · 2024Article
- Codesign of remote data collection for chronic management of pediatric home mechanical ventilation.Pediatric pulmonology · 2023Article
- Effects of the First Spontaneous Breathing Trial in Children With Tracheostomy and Long-Term Mechanical Ventilation.Respiratory care · 2023Observational
- Tracheostomy in Severe Bronchopulmonary Dysplasia-How to Decide in the Absence of Evidence.Biomedicines · 2023Review
- Respiratory Outcomes for Ventilator-Dependent Children With Bronchopulmonary Dysplasia.Pediatrics · 2023Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo describe the incidence and outcomes of children with chronic respiratory failure secondary to severe bronchopulmonary dysplasia (BPD) on chronic positive pressure ventilation (PPV) via tracheostomy at home.
methodsWe retrospectively reviewed medical charts of patients with severe BPD who were PPV dependent at home and who were enrolled in a university-affiliated home ventilator program between 1984 and 2010. We excluded patients with other comorbidities that could contribute to the development of chronic respiratory failure. We reported the incidence of these children in Indiana and cumulative incidences of survival, liberation from PPV, and decannulation.
resultsOver 27 years, 628 children were cared for in our home ventilator program. Of these, 102 patients met inclusion criteria: 83 (81.4%) were alive and 19 (18.6%) were deceased. Sixty-nine patients (67.6%) were liberated from PPV, and 97.1% of them were weaned before their fifth birthday, with a median age at liberation of 24 months (interquartile range, 19-33). Similarly, 60 patients (58.8%) were decannulated, of which 96.7% completed this process before their sixth birthday, with a median age at decannulation of 37.5 months (interquartile range, 31.5-45). The incidence of children with chronic respiratory failure secondary to BPD who were PPV-dependent at home in Indiana was 1.23 per 100 000 live births in 1984 and increased to 4.77 per 100 000 live births in 2010.
conclusionsAlthough extreme prematurity associated with severe BPD necessitating PPV at home carries significant risks of morbidity and mortality, successful liberation from mechanical ventilation and decannulation are likely to occur.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.