Evidence map›Paper›PMID 23918246›Full record

ArticleBioinformatics (Oxford, England)2013

MeltDB 2.0-advances of the metabolomics software system.

Nikolas Kessler, Heiko Neuweger, Anja Bonte, Georg Langenkämper, Karsten Niehaus, Tim W Nattkemper, Alexander Goesmann

Open access · bronzeAbstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 102 citations in OpenAlex.

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  3. CE-MS-Based Clinical Metabolomics of Human Plasma.Methods in molecular biology (Clifton, N.J.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nikolas KesslerBiodata Mining Group, CeBiTec, Bielefeld University, Bielefeld, Germany, Computational Genomics, CeBiTec, Bielefeld University, Bielefeld, Germany, Bruker Daltonik GmbH, Bremen, Germany, Proteome and Metabolome Research, Bielefeld University, Bielefeld, Germany and Max Rubner-Institute, Detmold, Germany.
Heiko Neuweger
Anja Bonte
Georg Langenkämper
Karsten Niehaus
Tim W Nattkemper
Alexander Goesmann
Bielefeld University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

motivationThe research area metabolomics achieved tremendous popularity and development in the last couple of years. Owing to its unique interdisciplinarity, it requires to combine knowledge from various scientific disciplines. Advances in the high-throughput technology and the consequently growing quality and quantity of data put new demands on applied analytical and computational methods. Exploration of finally generated and analyzed datasets furthermore relies on powerful tools for data mining and visualization.

resultsTo cover and keep up with these requirements, we have created MeltDB 2.0, a next-generation web application addressing storage, sharing, standardization, integration and analysis of metabolomics experiments. New features improve both efficiency and effectivity of the entire processing pipeline of chromatographic raw data from pre-processing to the derivation of new biological knowledge. First, the generation of high-quality metabolic datasets has been vastly simplified. Second, the new statistics tool box allows to investigate these datasets according to a wide spectrum of scientific and explorative questions. AVAILABILITY: The system is publicly available at https://meltdb.cebitec.uni-bielefeld.de. A login is required but freely available.

Indexed as

Software DesignCluster AnalysisDatabases, GeneticData MiningInternetMetabolomics

Identifiers

PMID23918246
PMCPMC3777109
OpenAlexW2148036820

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.