ArticleJournal of neural engineering2013
Selective activation of the human tibial and common peroneal nerves with a flat interface nerve electrode.
Article in Journal of neural engineering, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed.
- Biomimetic Peripheral Nerve Stimulation Promotes the Rat Hindlimb Motion Modulation in Stepping: An Experimental Analysis.Cyborg and bionic systems (Washington, D.C.) · 2024Article
- Fractal Microelectrodes for More Energy-Efficient Cervical Vagus Nerve Stimulation.Advanced healthcare materials · 2023Article
- Restoration of sensory information via bionic hands.Nature biomedical engineering · 2023Review
- Fascicles split or merge every ∼560 microns within the human cervical vagus nerve.Journal of neural engineering · 2022Article
- Examining theJournal of neural engineering · 2022Article
- Clinical Basis for Creating an Osseointegrated Neural Interface.Frontiers in neuroscience · 2022Article
- Wireless microelectrode arrays for selective and chronically stable peripheral nerve stimulation for hindlimb movement.Journal of neural engineering · 2021Article
- Selective neural stimulation methods improve cycling exercise performance after spinal cord injury: a case series.Journal of neuroengineering and rehabilitation · 2021Article
- Recent Developments in Prosthesis Sensors, Texture Recognition, and Sensory Stimulation for Upper Limb Prostheses.Annals of biomedical engineering · 2021Review
- Chronic nerve health following implantation of femoral nerve cuff electrodes.Journal of neuroengineering and rehabilitation · 2020Article
- Selective Nerve Cuff Stimulation Strategies for Prolonging Muscle Output.IEEE transactions on bio-medical engineering · 2020Article
- Sum of phase-shifted sinusoids stimulation prolongs paralyzed muscle output.Journal of neuroengineering and rehabilitation · 2020Article
- Image-guided focused ultrasound modulates electrically evoked motor neuronal activity in the mouse peripheral nervous system in vivo.Journal of neural engineering · 2020Article
- Intraoperative Responses May Predict Chronic Performance of Composite Flat Interface Nerve Electrodes on Human Femoral Nerves.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2019Article
- Real-Time Prosthetic Digit Actuation by Optical Read-out of Activity-Dependent Calcium Signals in an Ex Vivo Peripheral Nerve.International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering · 2019Article
- Distributed stimulation increases force elicited with functional electrical stimulation.Journal of neural engineering · 2018Article
- Tissue-Engineered Peripheral Nerve Interfaces.Advanced functional materials · 2018Article
- Optical read-out and modulation of peripheral nerve activity.Neural regeneration research · 2018Review
- A novel flexible cuff-like microelectrode for dual purpose, acute and chronic electrical interfacing with the mouse cervical vagus nerve.Journal of neural engineering · 2017Article
- Toward Bioelectronic Medicine-Neuromodulation of Small Peripheral Nerves Using Flexible Neural Clip.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveElectrical stimulation has been shown effective in restoring basic lower extremity motor function in individuals with paralysis. We tested the hypothesis that a flat interface nerve electrode (FINE) placed around the human tibial or common peroneal nerve above the knee can selectively activate each of the most important muscles these nerves innervate for use in a neuroprosthesis to control ankle motion. APPROACH: During intraoperative trials involving three subjects, an eight-contact FINE was placed around the tibial and/or common peroneal nerve, proximal to the popliteal fossa. The FINE's ability to selectively recruit muscles innervated by these nerves was assessed. Data were used to estimate the potential to restore active plantarflexion or dorsiflexion while balancing inversion and eversion using a biomechanical simulation. MAIN
resultsWith minimal spillover to non-targets, at least three of the four targets in the tibial nerve, including two of the three muscles constituting the triceps surae, were independently and selectively recruited in all subjects. As acceptable levels of spillover increased, recruitment of the target muscles increased. Selective activation of muscles innervated by the peroneal nerve was more challenging. SIGNIFICANCE: Estimated joint moments suggest that plantarflexion sufficient for propulsion during stance phase of gait and dorsiflexion sufficient to prevent foot drop during swing can be achieved, accompanied by a small but tolerable inversion or eversion moment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.