ReviewEcoHealth2013
Deciphering serology to understand the ecology of infectious diseases in wildlife.
Review in EcoHealth, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
111 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Pseudorabies virus in wild swine: current evidence and interpretations from monitoring studies.BMC veterinary research · 2026Pooled it
- Influence of Host and Landscape-Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals.Veterinary medicine and science · 2025Pooled it
- Temporal and spatial limitations in global surveillance for bat filoviruses and henipaviruses.Biology letters · 2019Pooled it
- Prioritizing surveillance of Nipah virus in India.PLoS neglected tropical diseases · 2019Pooled it
- Diversity of susceptible hosts in canine distemper virus infection: a systematic review and data synthesis.BMC veterinary research · 2016Pooled it
- A randomized, non-inferiority phase III clinical trial of immunogenicity and safety of 5-dose and 4-dose schedules of a freeze-dried human rabies vaccine (MRC-5 cells) in participants aged 10-60.BMC infectious diseases · 2025Trial
- Serological and transcriptomic response of African fruit bats to immune challenge with recombinant vaccines expressing Ebola or Nipah virus antigens.Royal Society open science · 2026Article
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- Article
- Simultaneous serological assessment of four zoonotic rickettsiae among dogs near the United States-Mexico border.PLoS neglected tropical diseases · 2026Article
- Serological evidence uncovers undocumented mpox exposure in febrile patients in Nigeria.Frontiers in public health · 2026Article
- Metagenomic survey reveals Volzhskoe tick virus inOne health (Amsterdam, Netherlands) · 2025Article
- Viral epidemic potential is not uniformly distributed across the bat phylogeny.Communications biology · 2025Article
- Surveillance Analysis and Sample Size Explorer (SASSE): Learning How to Plan Disease Surveillance in Wildlife.Ecology and evolution · 2025Article
- A novel method for estimating pathogen presence, prevalence, load, and dynamics at multiple scales.Scientific reports · 2025Article
- European distribution and intramuscular pathogenicity of divergent lyssaviruses West Caucasian bat virus and Lleida bat lyssavirus.iScience · 2025Article
- The Bacterial and pathogenic landscape of African buffalo (Syncerus caffer) whole blood and serum from Kenya.Animal microbiome · 2025Article
- Unique humoral immune response of pigs to repeated natural Japanese encephalitis virus infections: an amplifying host perspective.Archives of virology · 2025Article
- Tag, you're it!: viral diseases in native otters of south-central Chile due to coexistence with invasive American mink and domestic dogs.Frontiers in veterinary science · 2025Article
- Serodynamics: A primer and synthetic review of methods for epidemiological inference using serological data.Epidemics · 2024Review
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
The ecology of infectious disease in wildlife has become a pivotal theme in animal and public health. Studies of infectious disease ecology rely on robust surveillance of pathogens in reservoir hosts, often based on serology, which is the detection of specific antibodies in the blood and is used to infer infection history. However, serological data can be inaccurate for inference to infection history for a variety of reasons. Two major aspects in any serological test can substantially impact results and interpretation of antibody prevalence data: cross-reactivity and cut-off thresholds used to discriminate positive and negative reactions. Given the ubiquitous use of serology as a tool for surveillance and epidemiological modeling of wildlife diseases, it is imperative to consider the strengths and limitations of serological test methodologies and interpretation of results, particularly when using data that may affect management and policy for the prevention and control of infectious diseases in wildlife. Greater consideration of population age structure and cohort representation, serological test suitability and standardized sample collection protocols can ensure that reliable data are obtained for downstream modeling applications to characterize, and evaluate interventions for, wildlife disease systems.
Indexed as
Identifiers
23918033What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.