Evidence map›Paper›PMID 23917912›Full record

ArticleInfection control and hospital epidemiology2013

Prevalence and predictors of compliance with discontinuation of airborne isolation in patients with suspected pulmonary tuberculosis.

Benjamin S Thomas, Erlaine F Bello, Todd B Seto

Abstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Xpert MTB/RIF assay shortens airborne isolation for hospitalized patients with presumptive tuberculosis in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Benjamin S ThomasDivision of Infectious Diseases, Washington University School of Medicine, Saint Louis, Missouri, USA. bthomas@dom.wustl.edu
Erlaine F Bello
Todd B Seto

Funding

RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MOKUAU, NOREEN, SHIRAMIZU, BRUCE T · 2012 to 2018
$21.1M
RESEARCH ETHICSU54RR026136 · NCRR · UNIVERSITY OF HAWAII AT MANOA · PI INAZU, JUDITH · 2010 to 2011
$8.5M
NCRR NIH HHS U54 RR026136NCRR NIH HHS U54RR026136NIMHD NIH HHS U54 MD007584NIMHD NIH HHS U54MD007584
6 · The paper itself

Abstract

objectiveExamine the use of airborne isolation by identifying reasons for nontimely discontinuation and predictors of compliance with Centers for Disease Control and Prevention (CDC) guidelines. Compliance with guidelines should result in timely (within 48 hours) discontinuation of isolation in patients without infectious pulmonary tuberculosis (TB).

designRetrospective, observational study.

settingA private, university-affiliated, tertiary-care medical center. PATIENTS: All patients in airborne isolation for suspected pulmonary TB from June through December 2011.

methodChart reviews were performed to identify airborne isolation practices and delayed (greater than 48 hours) or very delayed (greater than 72 hours) discontinuation. We used descriptive statistics and logistic regression to determine independent predictors of nontimely discontinuation of isolation.

resultsWe identified 113 patients (mean age ± standard deviation, [Formula: see text] years; male sex, 75.2%; white race, 15.9%; mean collection interval ± standard deviation, [Formula: see text] hours). Delayed and very delayed isolation discontinuation was noted in 81% and 49% of patients, respectively. No significant differences in demographic characteristics and clinical characteristics were identified between groups. Predictors of timely (within 48 hours) airborne isolation discontinuation included use of alternate diagnosis for discontinuation of isolation ([Formula: see text]), early infectious diseases (ID) consultation ([Formula: see text]), pulmonary consultation ([Formula: see text]), average sputum collection interval less than 24 hours ([Formula: see text]), and need for more than 1 induced sputum specimen ([Formula: see text]). Adjusting for potential confounders, pulmonary consultation (odds ratio [OR] [95% confidence interval (CI)], 0.14 [0.03-0.58]), alternate diagnosis for discontinuation of isolation (OR [95% CI], 4.5 [1.3-15.8]), and early ID consultation (OR [95% CI], 4.0 [1.1-14.8]) were independently associated with timely discontinuation.

conclusionsTimely airborne isolation discontinuation occurs in only 18.6% of cases and is an opportunity for cost savings, improved efficiency, and potentially patient safety and satisfaction.

Indexed as

Cross InfectionFemaleGuideline AdherenceHawaiiHumansMaleMiddle AgedPatient IsolationPrevalenceRetrospective StudiesSputumTertiary Care CentersTime FactorsTuberculosis, Pulmonary

Identifiers

PMID23917912
PMCPMC3882086

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.