ReviewNature reviews. Neurology2013
Outcome predictors for status epilepticus--what really counts.
Review in Nature reviews. Neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it, 172 citations in OpenAlex.
- Pooled it
- Improving emergency management of status epilepticus: a randomized high-fidelity simulator-based trial.Journal of neurology · 2026Trial
- Development and validation of a nomogram to provide individualized predictions of functional outcomes in patients with convulsive status epilepticus at 3 months: The modified END-IT tool.CNS neuroscience & therapeutics · 2023Trial
- Prognostic Significance of Early Fever in Convulsive Status Epilepticus: Insights from the ICTAL Registry.Neurocritical care · 2026Article
- A Predictive Model for Short-Term Mortality After Status Epilepticus: The ACARD Score.Neurology · 2026Article
- Treatment adequacy outweighs treatment sequence in non-convulsive status epilepticus.Epilepsia · 2026Article
- Treatment outcome and its predictors among patients with status epilepticus in Africa: A systematic review and meta-analysis.Exploratory research in clinical and social pharmacy · 2026Review
- Article
- Quantitative assessment of apparent diffusion coefficient for neurological outcome prediction in status epilepticus: a pilot study.Scientific reports · 2026Article
- Observational
- Incidence, mortality, and management of status epilepticus from 2012 to 2022: An 11-year nationwide study.Epilepsia · 2026Article
- Cost-effectiveness analysis of a telemedicine network for acute neurological care in northeast Germany (ANNOTeM).Frontiers in digital health · 2026Article
- Evaluation and comparison of mortality scores in status epilepticus patients.BMC neurology · 2025Article
- Diagnosis, treatment, and outcome prediction of non-convulsive status epilepticus in unconscious patients in intensive care units.Neurological research and practice · 2025Review
- Fast Acute Sedation at Intensive Care vs. High-Dose IV Anti-seizure Medication for Treatment of Non-convulsive Status Epilepticus: A Randomized, Multicenter Trial.Critical care explorations · 2025Article
- Implementation of 2HELPS2B Seizure Risk Score: A Cost-Effective Approach to Seizure Detection in the Intensive Care Units.Neurology. Clinical practice · 2025Article
- Article
- Imaging of Status Epilepticus.Journal of clinical medicine · 2025Review
- Can the large language model ChatGPT-4omni predict outcomes in adult patients with status epilepticus?Epilepsia · 2025Article
- Hypoalbuminemia in status epilepticus is a biomarker of short- and long-term mortality: A 9-year cohort study.European journal of neurology · 2025Observational
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In adult patients with status epilepticus (SE)-a life-threatening state of ongoing or repetitive seizures--the current evidence regarding outcome prediction is based on clinical, biochemical and EEG determinants. These predictors of outcome involve clinical features such as age, history of prior seizures or epilepsy, SE aetiology, level of consciousness, and seizure type at SE onset. The clinical risk-benefit calculation between the danger of undertreated persistent seizure activity and, conversely, the potential damage from unwarranted aggressive treatments remains a constant challenge. Improved knowledge of outcome determinants, as well as increased availability of reliable outcome prediction models early in the course of SE, is paramount for optimization of treatment of patients who develop this disorder. In this Review, we discuss the major prognostic determinants of outcome in SE. Through consideration of studies that provide measures of association between predictors of SE outcome and death, we propose a detailed--but as yet unvalidated--paradigm for assessment of these predictors during the course of SE. Such an algorithm could guide the organization of results from existing trials and provide direction with regard to the parameters that should be monitored in future studies of SE.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.