ArticleClinics (Sao Paulo, Brazil)2013
Influence of obstructive sleep apnea on serum butyrylcholinesterase activity and ischemia-modified albumin levels.
Article in Clinics (Sao Paulo, Brazil), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Obstructive sleep apnea and the effect of CPAP treatment on ischemia-modified albumin levels: a multi effect size meta-analysis with diagnostic test accuracy.Sleep & breathing = Schlaf & Atmung · 2019Pooled it
- The Effect of Obstructive Sleep Apnea Surgery on Oxidative Stress Markers: A Prospective Observational Study.Journal of clinical medicine · 2026Article
- The effects of disease severity and comorbidity on oxidative stress biomarkers in obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2024Article
- Peripheral blood diagnostic markers of chronic cerebral hypoperfusion.American journal of translational research · 2024Article
- Analysis of the Ischemia-Modified Albumin as a Potential Biomarker for Cardiovascular Damage in Obstructive Sleep Apnea Patients with Acute Coronary Syndrome.International journal of molecular sciences · 2023Article
- Association between disease activity and ischaemia-modified albumin in patients with ulcerative colitis.Przeglad gastroenterologiczny · 2022Article
- Does ischemia-modified albumin level predict severity of obstructive sleep apnea?Sleep & breathing = Schlaf & Atmung · 2021Article
- The Impact of Obstructive Sleep Apnoea and Nasal Continuous Positive Airway Pressure on Circulating Ischaemia-Modified Albumin Concentrations.Mediators of inflammation · 2016Article
- Is there a dynamic change in ischemia-modified albumin in patients with obstructive sleep apnea, which often leads to ischemic diseases?Clinics (Sao Paulo, Brazil) · 2013Article
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4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the effect of obstructive sleep apnea and continuous positive airway pressure treatment on serum butyrylcholinesterase activity and ischemia-modified albumin levels.
methodsThirty-two patients with obstructive sleep apnea and 30 age- and sex-matched controls were enrolled and underwent a diagnostic polysomnogram. The serum butyrylcholinesterase activity, ischemia-modified albumin levels, metabolic parameters, and polysomnography scores were detected and evaluated. Nine patients were studied before and after treatment with continuous positive airway pressure.
resultsThe serum ischemia-modified albumin levels were significantly higher and the butyrylcholinesterase activity was significantly lower in patients with obstructive sleep apnea than in the controls (p<0.001). The continuous positive airway pressure treatment decreased the modified albumin levels and elevated the buthrylcholinesterase activity (p=0.019 and p=0.023, respectively). The modified albumin levels were positively correlated with the apnea-hypopnea index (r=0.462, p=0.008) at baseline. Elevated ischemia-modified albumin levels can be more accurate than butyrylcholinesterase activity at reflecting the presence of obstructive sleep apnea. Receiver operating characteristic curves revealed a significant difference between the areas under the curve 0.916 for ischemia-modified albumin and 0.777 for butyrylcholinesterase (z=2.154, p=0.031).
conclusionThe elevated ischemia-modified albumin level was significantly associated with obstructive sleep apnea and was more sensitive than butyrylcholinesterase activity in reflecting obstructive sleep apnea. The continuous positive airway pressure treatment helped to ameliorate the imbalance.
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