Evidence map›Paper›PMID 23916372›Full record

ReviewBlood cells, molecules & diseases2013

Assaying hematopoiesis using zebrafish.

Sonja Boatman, Francesca Barrett, Sruthi Satishchandran, Lili Jing, Ilya Shestopalov, Leonard I Zon

Open access · greenAbstract readReview
In one paragraph

Review in Blood cells, molecules & diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  7. Use of Zebrafish in Drug Discovery Toxicology.Chemical research in toxicology · 2020
    Review
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  20. Mechanical vessel injury in zebrafish embryos.Journal of visualized experiments : JoVE · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sonja BoatmanStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Harvard Medical School, Boston, MA, USA.
Francesca Barrett
Sruthi Satishchandran
Lili Jing
Ilya Shestopalov
Leonard I Zon
Boston Children's Hospital · USHarvard University · USHoward Hughes Medical Institute · US

Funding

EMBRYONIC HEMATOPOIESISR01HL048801 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI ZON, LEONARD IRA · 1992 to 2016
$5.7M
TEL GENE AND LEUKEMIASP50DK049216 · NIDDK · CHILDREN'S HOSPITAL BOSTON · PI ZON, LEONARD I · 1994 to 1998
–
Howard Hughes Medical InstituteNHLBI NIH HHS R01 HL048801NIDDK NIH HHS P50 DK049216
6 · The paper itself

Abstract

The zebrafish has become a commonly used model for studying hematopoiesis as a result of its unique attributes. Zebrafish are highly suitable for large-scale genetic and chemical screens compared to other vertebrate systems. It is now possible to analyze hematopoietic lineages in zebrafish and validate cell function via transplantation assays. Here, we review advancements over the past decade in forward genetic screens, chemical screens, fluorescence-activated cell sorting analysis, and transplantation assays. Integrating these approaches enables new chemical and genetic screens that assay cell function within the hematopoietic system. Studies in zebrafish will continue to contribute and expand our knowledge about hematopoiesis, and develop novel treatments for clinical applications.

Indexed as

AnimalsCell DifferentiationCell LineageHematopoiesisHematopoietic Stem CellsHematopoietic Stem Cell TransplantationHumansImmunophenotypingPhenotypeZebrafishAGMALManterior lateral mesodermaorta–gonad–mesonephrosBMbone marrowcaudal hematopoietic tissueCHTENUethylnitrosoureaFACSfluorescence-activated cell sortingforward light scatterFSCgraft-versus-host-diseaseGVHDhCBHCTHematopoiesishematopoietic cellular transplantationhours post fertilizationhpfhuman cord bloodICMintermediate cell massmajor histocompatibility complexMHCPAFPGPLMPol II Associated Factorposterior lateral mesodermprostaglandinScreensside light scatterSSCStem cellTGFβTIF1γtranscription intermediary factor1γtransforming growth factor betaTransplantationwhole kidney marrowWKMZebrafish

Identifiers

PMID23916372
PMCPMC3882012
OpenAlexW1965940508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.