Evidence map›Paper›PMID 23916188›Full record

Trial reportSchizophrenia research2013

Racial patterns of cardiovascular disease risk factors in serious mental illness and the overall U.S. population.

Tanya E Keenan, Airong Yu, Lisa A Cooper, Lawrence J Appel, Eliseo Guallar, Joseph V Gennusa, Faith B Dickerson, Rosa M Crum, Cheryl A Anderson, Leslie M Campbell and 2 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Schizophrenia research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Trial
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  11. Smoking and Mental Illness: A Bibliometric Analysis of Research Output Over Time.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Metabolic syndrome in patients with severe mental illness in Gorgan.Journal of natural science, biology, and medicine
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Tanya E KeenanWelch Center for Prevention, Epidemiology, and Clinical Research, The Johns Hopkins Medical Institutions, 2024 E. Monument Street, Baltimore, MD 21205, USA. Electronic address: keenant@mail.med.upenn.edu.
Airong Yu
Lisa A Cooper
Lawrence J Appel
Eliseo Guallar
Joseph V Gennusa
Faith B Dickerson
Rosa M Crum
Cheryl A Anderson
Leslie M Campbell
Deborah R Young
Gail L Daumit
Johns Hopkins University · USJohns Hopkins Medicine · USKaiser Permanente · USSheppard Pratt Health System · US

Funding

TRAINING COREP50HL105187 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI GOLDEN, SHERITA HILL · 2010 to 2014
$9.8M
Randomized Trial of Achieving Healthy Lifestyles in Psych RehabilitationR01MH080964 · NIMH · JOHNS HOPKINS UNIVERSITY · PI DAUMIT, GAIL L. · 2008 to 2012
$5.2M
IMPLEMENTATION RESEARCH INSTITUTE FOR MENTAL HEALTH SERVICES IRI-MHSR25MH080916 · NIMH · WASHINGTON UNIVERSITY · PI Byron James Powell · 2009 to 2026
$3.7M
Patient-Oriented Research in Cardiovascular DisparitiesK24HL083113 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI COOPER, LISA A · 2006 to 2015
$2.0M
Developing and Translating Interventions to Decrease Mortality Disparities in SMIK24MH093763 · NIMH · JOHNS HOPKINS UNIVERSITY · PI DAUMIT, GAIL L. · 2012 to 2016
$830k
NHLBI NIH HHS K24 HL083113NHLBI NIH HHS P50 HL0105187NHLBI NIH HHS P50 HL105187NIMH NIH HHS K24 MH093763NIMH NIH HHS R01 MH080964NIMH NIH HHS R01MH080964NIMH NIH HHS R25 MH080916
6 · The paper itself

Abstract

backgroundSerious mental illness (SMI) and minority race are each associated with elevated cardiovascular disease (CVD) mortality. However, little is known about racial variation in CVD risk factors in individuals with SMI. This study aimed to determine racial patterns of CVD risk factors in individuals with SMI and to compare these patterns to those of the general population.

methodsOverweight/obese adults with SMI (163 whites; 111 African Americans) examined from 2008 to 2011 during a weight loss trial were compared at study baseline to overweight/obese adults (1103 whites; 550 African Americans) of similar age, sex, and race in the 2007 to 2010 National Health and Nutrition Examination Survey.

resultsAll CVD risk factors except cholesterol were higher in SMI than the overall U.S. population. After adjusting for age and sex, both racial groups with SMI had similarly high risks of smoking, obesity, diabetes, and hypertension, while African Americans with SMI had lower risks of high cholesterol (RR 0.73; 95% CI 0.57-0.94) and metabolic syndrome (RR 0.75; 95% CI 0.63-0.91) than whites with SMI. In the U.S. population sample, African Americans compared to whites had higher risks of obesity (RR 1.23; 95% CI 1.14-1.34), diabetes (RR 1.68; 95% CI 1.21-2.34), and hypertension (RR 1.44; 95% CI 1.31-1.60) but no significant difference in smoking, high cholesterol, and metabolic syndrome.

conclusionsCompared to the general population, the greater burden and dissimilar racial pattern of CVD risk factors in SMI underscore the need for CVD prevention programs targeting the SMI population.

Indexed as

AdultBlack or African AmericanCardiovascular DiseasesFemaleHealth SurveysHumansMaleMental DisordersMiddle AgedRetrospective StudiesRisk FactorsUnited StatesWhite PeopleCardiovascular disease risk factorsDiabetesHypertensionObesityRacial disparitiesSerious mental illness

Identifiers

PMID23916188
PMCPMC3821976
OpenAlexW2004129888

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.