ArticleThe Journal of allergy and clinical immunology2014
Neonatal health of infants born to mothers with asthma.
Article in The Journal of allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Interventions for managing asthma in pregnancy.The Cochrane database of systematic reviews · 2014Pooled it
- The association of exhaled nitric oxide with air pollutants in young infants of asthmatic mothers.Environmental health : a global access science source · 2023Trial
- Effect of Nursing Intervention Supported by Mobile Health Applications on Asthma Control, Maternal and Neonatal Outcomes Among Pregnant Women with Asthma.Healthcare (Basel, Switzerland) · 2026Article
- Altered expression of Toll-like receptor 9 in the lung tissue of adult mice generated by in vitro embryo culture and embryo transfer.Histochemistry and cell biology · 2026Article
- Early-life lung function deficits partially explain the link between maternal asthma and bronchiolitis or asthma in offspring.BMJ open respiratory research · 2026Article
- Sex, hormones, and lung health.Physiological reviews · 2026Review
- Neonatal meconium aspiration syndrome with transient Hyperreactive airways and socioeconomic challenges: a case report.Oxford medical case reports · 2025Article
- Maternal asthma during pregnancy and the likelihood of neurodevelopmental disorders in offspring.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review).Experimental and therapeutic medicine · 2024Review
- Betamethasone improved near-term neonatal lamb lung maturation in experimental maternal asthma.Experimental physiology · 2024Article
- Preclinical models of maternal asthma and progeny outcomes: a scoping review.European respiratory review : an official journal of the European Respiratory Society · 2024Article
- Maternal asthma in relation to infant size and body composition.The journal of allergy and clinical immunology. Global · 2023Article
- Article
- Determining the Clinical Course of Asthma in Pregnancy.The journal of allergy and clinical immunology. In practice · 2022Article
- Risk Factors of Childhood Asthma Among Patients Attending a Tertiary Care Centre in North-East India.Journal of asthma and allergy · 2022Article
- Maternal body composition and gestational weight gain in relation to asthma control during pregnancy.PloS one · 2022Article
- Sex and gender in asthma.European respiratory review : an official journal of the European Respiratory Society · 2021Review
- Environmental Air Pollutants Inhaled during Pregnancy Are Associated with Altered Cord Blood Immune Cell Profiles.International journal of environmental research and public health · 2021Article
- Role of Sex Hormones at Different Physiobiological Conditions and Therapeutic Potential in MBD2 Mediated Severe Asthma.Oxidative medicine and cellular longevity · 2021Review
- Recent Advances in Pathophysiology and Management of Transient Tachypnea of Newborn.Journal of perinatology : official journal of the California Perinatal Association · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundMaternal asthma is associated with serious pregnancy complications, but newborn morbidity is understudied.
objectiveWe wanted to determine whether infants of asthmatic mothers have more neonatal complications.
methodsThe Consortium on Safe Labor (2002-2008), a retrospective cohort, included 223,512 singleton deliveries at ≥ 23 weeks' gestation. Newborns of mothers with asthma (n = 17,044) were compared with newborns of women without asthma by using logistic regression models with generalized estimating equations to calculate adjusted odds ratios (ORs) and 95% CIs. Electronic medical record data included gestational week at delivery, birth weight, resuscitation, neonatal intensive care unit (NICU) admission, NICU length of stay, hyperbilirubinemia, respiratory distress syndrome, apnea, sepsis, anemia, transient tachypnea of the newborn, infective pneumonia, asphyxia, intracerebral hemorrhage, seizure, cardiomyopathy, periventricular or intraventricular hemorrhage, necrotizing enterocolitis, aspiration, retinopathy of prematurity, and perinatal mortality.
resultsPreterm delivery was associated with maternal asthma for each week after 33 completed weeks of gestation and not earlier. Maternal asthma also increased the adjusted odds of small for gestational age (OR = 1.10; 95% CI, 1.05-1.16), NICU admission (OR = 1.12; 95% CI, 1.07-1.17), hyperbilirubinemia (OR = 1.09; 95% CI, 1.04-1.14), respiratory distress syndrome (OR = 1.09; 95% CI, 1.01-1.19), transient tachypnea of the newborn (OR = 1.10; 95% CI, 1.02-1.19), and asphyxia (OR = 1.34; 95% CI, 1.03-1.75). Findings persisted for term infants (≥ 37 weeks) who had additional increased odds of intracerebral hemorrhage (OR = 1.84; 95% CI, 1.11-3.03) and anemia (OR = 1.30; 95% CI, 1.04-1.62).
conclusionsMaternal asthma was associated with prematurity and small for gestational age. Adverse neonatal outcomes, including respiratory complications, hyperbilirubinemia, and NICU admission, were increased in association with maternal asthma even among term deliveries.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.