ArticleMedical gas research2013
Volatile anesthetics-induced neuroinflammatory and anti-inflammatory responses.
Article in Medical gas research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02229201 (Phase 1 Study of the Impact of Propofol vs. Sevoflurane on Brain Damage and Inflammatory Response During Brain Tumour Surgery), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Phase 1 Study of the Impact of Propofol vs. Sevoflurane on Brain Damage and Inflammatory Response During Brain Tumour Surgery
Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Effect of propofol and sevoflurane on the inflammatory response of patients undergoing craniotomy.BMC anesthesiology · 2016Trial
- Sedation as an Immunomodulator of Inflammatory Responses in the Lung-Brain Axis of ARDS.International journal of molecular sciences · 2026Review
- Salivary Substance P Levels During Cesarean Section Under Spinal versus General Anesthesia: A Prospective Study.Journal of pain research · 2026Article
- Relationship between volatile anesthetics and functional outcomes in patients with subarachnoid hemorrhage.Journal of anesthesia, analgesia and critical care · 2025Article
- Effects of Volatile Anaesthetics and Iron Dextran on Chronic Inflammation and Antioxidant Defense System in Rats.Antioxidants (Basel, Switzerland) · 2022Article
- Transcriptomic response of brain tissue to focused ultrasound-mediated blood-brain barrier disruption depends strongly on anesthesia.Bioengineering & translational medicine · 2021Article
- Article
- Involvement of acute neuroinflammation in postoperative delirium-like cognitive deficits in rats.Journal of anesthesia · 2018Article
- Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats via Suppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury.Translational stroke research · 2018Article
- Anti-inflammatory properties of anesthetic agents.Critical care (London, England) · 2017Review
- Dexmedetomidine Postconditioning Reduces Brain Injury after Brain Hypoxia-Ischemia in Neonatal Rats.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2016Article
- Transfusion of Old RBCs Induces Neuroinflammation and Cognitive Impairment.Critical care medicine · 2015Article
- Plasma kynurenic acid concentration in patients undergoing cardiac surgery: effect of anaesthesia.Archivum immunologiae et therapiae experimentalis · 2015Article
- The choice of general anesthetics may not affect neuroinflammation and impairment of learning and memory after surgery in elderly rats.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2015Article
- A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice.PloS one · 2015Article
- Olfactory bulbectomy leads to prolonged induction phase of sevoflurane anesthesia in rats.Medical gas researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Volatile anesthetics have been the major anesthetics used clinically for more than 150 years. They provide all components of general anesthesia and are easy to be applied and monitored with modern equipment and technology. In addition to having anesthetic property, volatile anesthetics have multiple other effects. Many studies have clearly shown that volatile anesthetics can reduce systemic and local inflammatory responses induced by various stimuli in humans and animals. On the other hand, recent animal studies have shown that volatile anesthetics may induce mild neuroinflammation. These dual effects on inflammation may have significant biological implications and are briefly reviewed here.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.