Evidence map›Paper›PMID 23915183›Full record

ArticleReproductive biology and endocrinology : RB&E2013

Analysis of oxidative stress during the menstrual cycle.

Umberto Cornelli, Gianni Belcaro, Maria Rosaria Cesarone, Annarosa Finco

Registry-linked trialAbstract read
In one paragraph

Article in Reproductive biology and endocrinology : RB&E, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05028959 (Menstrual Cycle, Amenorrhea and Contraception in Elite Female Athletes), which is not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05028959 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Menstrual Cycle, Amenorrhea and Contraception in Elite Female Athletes: Impact on Performance, Health and the Athlete's Biological Passport

TypeinterventionalSponsorUniversité Paris-Saclay-Assistance publique des hôpitaux de ParisRan2021 to 2025Enrolled80ConditionsHealthyArmsMultidisciplinary monitoring of healthy women
3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Umberto CornelliLoyola University School of Medicine-Chicago, Chicago, USA.
Gianni Belcaro
Maria Rosaria Cesarone
Annarosa Finco

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew data concerning the oxidative stress (OS) in plasma during the entire menstrual cycle of eumenorrheic women are available.

methodsOS was assessed in 20 healthy volunteers during the phase of the menstrual cycle by determining the plasmatic hydroperoxides levels (d-ROMs test). The assessment was performed every three days, starting from the first day (t1) up the end of the menstrual phase (t27). Concomitantly, the estrogen (E2) and progestin (P4) levels were determined at the same time intervals.

resultsFrom a base value (t1) of 284 +/- 38.0 CARR.U., which is essentially within the normal range (<300 Carratelli units or CARR.U.), the OS levels progressively increased to 378 +/- 115 CARR.U. at t15, and then slightly decreased over the subsequent time but with average values >300 CARR.U. Analysis of the E2 levels showed that the maximum OS values were noticed near the estrogen peak, while remaining above the base levels, and then decreased during the progestin phase until returning to normal at the end of the menstrual cycle.

conclusionsIt may concludes that the healthy women go into OS for 2/3 of the menstrual cycle.

Indexed as

Oxidative StressAdultEstradiolFemaleHumansLuteinizing HormoneMalondialdehydeMenstrual CycleProgesteroneReactive Oxygen SpeciesThiobarbituric Acid Reactive SubstancesEstradiolLuteinizing HormoneMalondialdehydeProgesteroneReactive Oxygen SpeciesThiobarbituric Acid Reactive Substances

Identifiers

PMID23915183
PMCPMC3765217

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.