Evidence map›Paper›PMID 23915047›Full record

ArticleACS applied materials & interfaces2013

Nitric oxide-releasing silica nanoparticle-doped polyurethane electrospun fibers.

Ahyeon Koh, Alexis W Carpenter, Danielle L Slomberg, Mark H Schoenfisch

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Mechanisms of Foreign Body Response Mitigation by Nitric Oxide Release.International journal of molecular sciences · 2022
    Article
  3. Article
  4. Electrospun Bioabsorbable Fibers ContainingACS applied bio materials · 2020
    Article
  5. Review
  6. Nitric Oxide Therapy for Diabetic Wound Healing.Advanced healthcare materials · 2019
    Review
  7. Article
  8. Article
  9. Article
  10. Synthesis and Characterization of a FluorinatedJournal of materials chemistry. B · 2018
    Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ahyeon KohDepartment of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
Alexis W Carpenter
Danielle L Slomberg
Mark H Schoenfisch

Funding

Nitric Oxide-Releasing Glucose BiosensorsR01EB000708 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SCHOENFISCH, MARK H · 2002 to 2011
$3.1M
NIBIB NIH HHS EB000708NIBIB NIH HHS R01 EB000708
6 · The paper itself

Abstract

Electrospun polyurethane fibers doped with nitric oxide (NO)-releasing silica particles are presented as novel macromolecular scaffolds with prolonged NO-release and high porosity. Fiber diameter (119-614 nm) and mechanical strength (1.7-34.5 MPa of modulus) were varied by altering polyurethane type and concentration, as well as the NO-releasing particle composition, size, and concentration. The resulting NO-releasing electrospun nanofibers exhibited ~83% porosity with flexible plastic or elastomeric behavior. The use of N-diazeniumdiolate- or S-nitrosothiol-modified particles yielded scaffolds exhibiting a wide range of NO release totals and durations (7.5 nmol mg(-1)-0.12 μmol mg(-1) and 7 h to 2 weeks, respectively). The application of NO-releasing porous materials as coatings for subcutaneous implants may improve tissue biocompatibility by mitigating the foreign body response and promoting cell integration.

Indexed as

Azo CompoundsBiocompatible MaterialsHumansNanofibersNanoparticlesNitric OxidePolyurethanesPorositySilicon DioxideAzo CompoundsBiocompatible MaterialsdiazeniumdiolateNitric OxidePolyurethanesSilicon Dioxide

Identifiers

PMID23915047
PMCPMC3811043

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.