ArticleWorld journal of surgical oncology2013
Giant gastrointestinal stromal tumor (GIST) of the stomach cause of high bowel obstruction: surgical management.
Article in World journal of surgical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 32 citations in OpenAlex.
- Article
- Article
- Do you get the GIST? Successful resection of a giant 3.5 kg gastrointestinal stromal tumour.ANZ journal of surgery · 2022Article
- Primary mesenteric gastrointestinal stromal tumor presented with acute small bowel obstruction.Journal of surgical case reports · 2020Article
- A Huge Pelvic-Abdominal Malignant GIST Tumour in a Patient with Neurofibromatosis Type 1: Case Report and Literature Review.Case reports in oncological medicine · 2020Article
- Giant gastrointestinal stromal tumour of the stomach: a case report with surgical treatment.Annals of the Royal College of Surgeons of England · 2018Article
- Functional Changes Induced by Orexin A and Adiponectin on the Sympathetic/Parasympathetic Balance.Frontiers in physiology · 2018Article
- Giant gastric gastrointestinal stromal tumor with severe peritoneal dissemination controlled by imatinib therapy following debulking surgery: a case report.Journal of medical case reports · 2017Article
- Using endoscopy to minimize the extent of resection in the management of giant GISTs of the stomach.International journal of surgery case reports · 2017Article
- Laparoscopy-assisted resection of CD117 and CD34 negative gastrointestinal tumor of stomach following tyrosine kinase inhibitor therapy.Medical journal, Armed Forces India · 2016Article
- Treatment and Prognoses in Patients With Primary Gastrointestinal Stromal Tumors ≥10 cm: A Single-Institution Experience in China.Medicine · 2015Observational
- Giant gastrointestinal stromal tumour of rare sarcomatoid epithelioid subtype: case study and literature review.World journal of gastroenterology · 2015Review
- A rare case of giant gastrointestinal stromal tumor of the stomach involving the serosal surface.International journal of surgery case reports · 2015Article
- Management of a Gastrobronchial Fistula Connected to the Skin in a Giant Extragastric Stromal Tumor.Case reports in surgery · 2015Article
- Giant exophytic gastrointestinal stromal tumor (GIST) causing gastric outlet obstruction: case report and review of literature.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieReview
- A Giant Gastrointestinal Stromal Tumor of the Stomach with Extramural Growth.Case reports in gastroenterologyArticle
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGastrointestinal stromal tumors (GISTs) represent 85% of all mesenchymal neoplasms that affect the gastrointestinal (GI) tract. These GISTs range in size from small lesions to large masses. Often they are clinically silent until they reach a significant size, so their discovery is usually incidental. CASE PRESENTATION: A 67-year-old man was admitted at our general surgery department with a persistent abdominal pain in the left hypochondrium, associated with nausea and vomiting. Clinical examination revealed a palpable mass in the epigastrium and in the left hypochondrium, which was approximately 40 cm long. Ultrasonography and computed tomography of the abdomen showed a large mass of 40 × 25 cm, which extended from the posterior wall of the stomach to the spleen, involving the body and the tail of the pancreas. The patient underwent en-block resection of the mass, sleeve resection of the stomach, and distal pancreatectomy-splenectomy. The histopathology of the resected specimen was consistent with a gastrointestinal stromal tumor of the stomach (positive for CD 117) with a high risk of malignancy (mitotic count >5/50 high-power fieldand Ki67/Mib1 >10%). The postoperative course was uneventful and treatment with imatinib mesylate began immediately. The patient appears to be disease free after four years.
conclusionsGiant GISTs of the stomach are rare. Surgical resection with curative intent is feasible. The combination of surgical resection and imatinib can provide long-termdisease-free survival. An R0 resection is the best achievable treatment, therefore the patient should be evaluated over time for potential resectability.
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