Evidence map›Paper›PMID 23913918›Full record

ArticleGenes & development2013

How mammals pack their sperm: a variant matter.

Ana Boskovic, Maria-Elena Torres-Padilla

Abstract readComment
In one paragraph

Article in Genes & development, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. International journal of molecular sciences · 2024
    Article
  2. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ana BoskovicU964, Institut National de la Santé et de la Recherche Médicale INSERM, Centre National de la Recherche Scientifique CNRS, Institut de Génétique et de Biologie Moléculaire et Cellulaire, F-67404 Illkirch, Cu de Strasbourg, France.
Maria-Elena Torres-Padilla

Funding

European Research Council 280840
6 · The paper itself

Abstract

Producing competent gametes is essential for transmitting genetic information throughout generations. Spermatogenesis is a unique example of rearrangements of genome packaging to ensure fertilization. After meiosis, spermatids undergo drastic morphological changes, perhaps the most dramatic ones occurring in their nuclei, including the transition into a protamine-packaged genome. In this issue of Genes & Development, Montellier and colleagues (pp. 1680-1692) shed new light on the molecular mechanisms regulating this transition by ascribing for the first time a function to a histone variant, TH2B, in the regulation of this process.

Indexed as

AnimalsChromatinFemaleHistonesMaleProtaminesChromatindeoxyribonucleoprotaminehistone H2B type 1-AHistonesProtaminesBRDTH2AZhistone evictionmale contraceptionmale infertilityreprogrammingsex chromosome inactivation

Identifiers

PMID23913918
PMCPMC3744721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.