ArticleBMJ case reports2013
A complex neurological presentation of syphilis.
Article in BMJ case reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Acute neurosyphilis as a cause of death in the 21st century - autopsy case report in a prisoner.Forensic science, medicine, and pathology · 2026Article
- The Great Imitator: A Case of Secondary Neurosyphilis With Unusual Neurological Manifestations.Cureus · 2025Article
- Neurosyphilis in AIDS patient presenting as isolated cranial nerve 6 palsy.Clinical case reports · 2020Article
- Acute cranial neuropathies heralding neurosyphilis in human immunodeficiency virus-infected patient.The American journal of case reports · 2014Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Syphilis is a contagious sexually transmitted infection notable for its complex array of systemic presentations. It is caused by the spirochaete Treponema pallidum and although once considered to be a largely historical condition in the UK, the recent rise in incidence makes syphilis increasingly relevant when considering unusual presentations in at-risk patients. The disease has three stages: primary, secondary and tertiary. The tertiary stage is associated with a plethora of neurological features ranging from psychosis to seizure caused by direct invasion of the spirochaete into the central nervous system. Here we describe the case of a 45-year-old man presenting with tonic clonic seizures on a background of balance and visual problems. Following normal examination and routine investigations further serology confirmed a diagnosis of neurosyphilis. The patient was started on appropriate treatment and made an excellent clinical recovery.
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