ArticleLipids2013
Fatty acid profile of the initial oral biofilm (pellicle): an in-situ study.
Article in Lipids, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 42 citations in OpenAlex.
- Bovine milk and milk protein- promotor or inhibitor of bacterial biofilm formation at the tooth surface?BMC oral health · 2025Article
- Acquired pellicle engineering: a fascinating approach to prevent demineralization.Journal of applied oral science : revista FOB · 2025Review
- In Vitro and In Silico Studies of the Antimicrobial Activity of Prenylated Phenylpropanoids of Green Propolis and Their Derivatives against Oral Bacteria.Antibiotics (Basel, Switzerland) · 2024Article
- Surface Topography Has Less Influence on Peri-Implantitis than Patient Factors: A Comparative Clinical Study of Two Dental Implant Systems.ACS biomaterials science & engineering · 2024Article
- Sensors for in situ monitoring of oral and dental health parameters in saliva.Clinical oral investigations · 2023Review
- Salivary pellicle modulates biofilm formation on titanium surfaces.Clinical oral investigations · 2023Article
- The composition of the dental pellicle: an updated literature review.Frontiers in oral health · 2023Review
- Rinsing solutions containing natural extracts and fluoride prevent enamel erosion in vitro.Journal of applied oral science : revista FOB · 2023Article
- Modification of the Lipid Profile of the Initial Oral Biofilm In Situ Using Linseed Oil as Mouthwash.Nutrients · 2021Article
- Acquired salivary pellicle and oral diseases: A literature review.Journal of dental sciences · 2021Review
- Targeted metabolomics of pellicle and saliva in children with different caries activity.Scientific reports · 2020Article
- Effects of water-aging for 6 months on the durability of a novel antimicrobial and protein-repellent dental bonding agent.International journal of oral science · 2018Article
- The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity.Scientific reports · 2017Article
- Effects of Long-Term Water-Aging on Novel Anti-Biofilm and Protein-Repellent Dental Composite.International journal of molecular sciences · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The first step of bioadhesion on dental surfaces is the formation of the acquired pellicle. This mainly acellular layer is formed instantaneously on all solid surfaces exposed to oral fluids. It is composed of proteins, glycoproteins and lipids. However, information on the lipid composition is sparse. The aim of the present study was to evaluate the fatty acid (FA) profile of the in-situ pellicle for the first time. Furthermore, the impact of rinses with safflower oil on the pellicle's FA composition was investigated. Pellicles were formed in situ on bovine enamel slabs mounted on individual upper jaw splints. The splints were carried by ten subjects over durations of 3-240 min. After comprehensive sample preparation, gas chromatography coupled with electron impact ionization mass spectrometry (GC-EI/MS) was used in order to characterize qualitatively and quantitatively a wide range of FA (C12-C24). The relative FA profiles of the pellicle samples gained from different subjects were remarkably similar, whereas the amount of FA showed significant interindividual variability. An increase in FA in the pellicle was observed over time. The application of rinses with safflower oil resulted in an accumulation of its specific FA in the pellicle. Pellicle formation is a highly selective process that does not correlate directly with salivary composition, as shown for FA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.