Trial reportJournal of diabetes science and technology2013
Susceptibility of interstitial continuous glucose monitor performance to sleeping position.
Trial report in Journal of diabetes science and technology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Perioperative use and accuracy of continuous glucose monitoring: A systematic review.Diabetes, obesity & metabolism · 2025Pooled it
- Continuous Glucose Monitors and Automated Insulin Dosing Systems in the Hospital Consensus Guideline.Journal of diabetes science and technology · 2020Guideline
- Glycaemic Impact of Low- and High-Glycaemic Index Carbohydrate Diets in Ultra-Endurance Athletes: Insights From Continuous Glucose Monitoring.European journal of sport science · 2025Trial
- Continuous glucose monitoring in patients with post-bariatric hypoglycaemia reduces hypoglycaemia and glycaemic variability.Diabetes, obesity & metabolism · 2023Trial
- Workshop on Noninvasive Glucose Monitoring 2025.Journal of diabetes science and technology · 2026Article
- Evaluating Continuous Glucose Monitoring (CGM) Derived Glucose Variability in Athletes Clinically Diagnosed With Relative Energy Deficiency in Sport (REDs).European journal of sport science · 2026Article
- Challenges of Wearable Biosensors and Ways to Overcome Them.Biosensors · 2026Review
- Injury to tissue caused by device penetration of the skin triggers formation of extracellular traps.Communications biology · 2025Article
- Diabetes Mellitus in Pregnancy: Implications for Obstetric Anesthesia.Anesthesiology · 2025Review
- Non-Diabetic Hypoglycemia: Evaluation and Management in Adults.Journal of clinical medicine · 2025Review
- Perioperative use of flash glucose monitoring system in dogs undergoing general surgery: a clinical feasibility study.Journal of veterinary science · 2025Article
- Toward Automation: The Road Traveled and Road Ahead for Integrating Automated Insulin Delivery into Inpatient Care.Diabetes technology & therapeutics · 2025Review
- Glucose interpretation meaning and action: enhancing type 1 diabetes decision-making with textual descriptions.Therapeutic advances in endocrinology and metabolism · 2025Article
- Simulating Realistic Continuous Glucose Monitor Time Series By Data Augmentation.Journal of diabetes science and technology · 2025Article
- Continuous glucose monitoring in para cyclists: An observational study.European journal of sport science · 2024Observational
- [The impact of remote monitoring of glycemia self-control on carbohydrate metabolism and quality of life in patients with type 1 diabetes mellitus].Problemy endokrinologii · 2024Article
- Continuous measurement of interstitial glycaemia in professional female UCI world tour cyclists undertaking a 9-day cycle training camp.European journal of sport science · 2024Article
- Hydrogel-based approaches to target hypersensitivity mechanisms underlying autoimmune disease.Advanced drug delivery reviews · 2024Review
- A Glucose-Responsive Cannula for Automated and Electronics-Free Insulin Delivery.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Continuous glucose monitor accuracy during extracorporeal membrane oxygenation.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDeveloping a round-the-clock artificial pancreas requires accurate and stable continuous glucose monitoring. The most widely used continuous glucose monitors (CGMs) are percutaneous, with the sensor residing in the interstitial space. Inaccuracies in percutaneous CGM readings during periods of lying on the devices (e.g., in various sleeping positions) have been anecdotally reported but not systematically studied.
methodsIn order to assess the impact of sleep and sleep position on CGM performance, we conducted a study in human subjects in which we measured the variability of interstitial CGM data at night as a function of sleeping position. Commercially available sensors were placed for 4 days in the abdominal subcutaneous tissue in healthy, nondiabetic volunteers (four sensors per person, two per side). Nocturnal sleeping position was determined from video recordings and correlated to sensor data.
resultsWe observed that, although the median of the four sensor readings was typically 70-110 mg/dl during sleep, individual sensors intermittently exhibited aberrant glucose readings (>25 mg/dl away from median) and that these aberrant readings were strongly correlated with subjects lying on the sensors. We expected and observed that most of these aberrant sleep-position-related CGM readings were sudden decreases in reported glucose values, presumably due to local blood-flow decreases caused by tissue compression. Curiously, in rare cases, the aberrant CGM readings were elevated values.
conclusionsThese findings highlight limitations in our understanding of interstitial fluid physiology in the subcutaneous space and have significant implications for the utilization of sensors in the construction of an artificial pancreas.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.