Evidence map›Paper›PMID 23910689›Full record

ArticleThe Journal of allergy and clinical immunology2014

A simulation model of building intervention impacts on indoor environmental quality, pediatric asthma, and costs.

Maria Patricia Fabian, Gary Adamkiewicz, Natasha Kay Stout, Megan Sandel, Jonathan Ian Levy

Abstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Climate and health benefits of a transition from gas to electric cooking.Proceedings of the National Academy of Sciences of the United States of America · 2023
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  8. Review
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  12. Difficult-to-control asthma: epidemiology and its link with environmental factors.Current opinion in allergy and clinical immunology · 2015
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria Patricia FabianDepartment of Environmental Health, Boston University School of Public Health, Boston, Mass; Department of Environmental Health, Harvard School of Public Health, Boston, Mass. Electronic address: pfabian@bu.edu.
Gary AdamkiewiczDepartment of Environmental Health, Harvard School of Public Health, Boston, Mass.
Natasha Kay StoutDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Mass.
Megan SandelDepartment of General Pediatrics, Boston Medical University School of Medicine, Boston, Mass.
Jonathan Ian LevyDepartment of Environmental Health, Boston University School of Public Health, Boston, Mass; Department of Environmental Health, Harvard School of Public Health, Boston, Mass.

Funding

A Discrete Event Simulation Model of Environmental Exposures and Pediatric AsthmaR21ES017522 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI LEVY, JONATHAN I · 2009 to 2010
$491k
NIEHS NIH HHS R21 ES017522NIEHS NIH HHS R21ES017522
6 · The paper itself

Abstract

backgroundAlthough indoor environmental conditions can affect pediatric asthmatic patients, few studies have characterized the effect of building interventions on asthma-related outcomes. Simulation models can evaluate such complex systems but have not been applied in this context.

objectiveWe sought to evaluate the impact of building interventions on indoor environmental quality and pediatric asthma health care use, and to conduct cost comparisons between intervention and health care costs and energy savings.

methodsWe applied our previously developed discrete event simulation model (DEM) to simulate the effect of environmental factors, medication compliance, seasonality, and medical history on (1) pollutant concentrations indoors and (2) asthma outcomes in low-income multifamily housing. We estimated health care use and costs at baseline and subsequent to interventions, and then compared health care costs with energy savings and intervention costs.

resultsInterventions, such as integrated pest management and repairing kitchen exhaust fans, led to 7% to 12% reductions in serious asthma events with 1- to 3-year payback periods. Weatherization efforts targeted solely toward tightening a building envelope led to 20% more serious asthma events, but bundling with repairing kitchen exhaust fans and eliminating indoor sources (eg, gas stoves or smokers) mitigated this effect.

conclusionOur pediatric asthma model provides a tool to prioritize individual and bundled building interventions based on their effects on health and costs, highlighting the tradeoffs between weatherization, indoor air quality, and health. Our work bridges the gap between clinical and environmental health sciences by increasing physicians' understanding of the effect that home environmental changes can have on their patients' asthma.

Indexed as

Computer SimulationModels, BiologicalAir PollutantsAir Pollution, IndoorAsthmaChildChild, PreschoolCosts and Cost AnalysisFemaleHumansMaleParticulate MatterPest ControlAir PollutantsParticulate MatterAir pollutionallergenasthmaDEMdiscrete event simulationDiscrete event simulation modelEDEmergency departmentenergy savingsFEV(1)%green buildinghousingindoor airIntegrated pest managementinterventionIPMlung functionMedical Expenditure Panel SurveyMEPSNitrogen dioxideNO(2)Particulate matter less than 2.5 μm in diameterPercent predicted forced expiratory volume in 1 secondPM(2.5)

Identifiers

PMID23910689
PMCPMC3874261

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.