ArticleThe EMBO journal1990
Cloning and expression of eukaryotic initiation factor 4B cDNA: sequence determination identifies a common RNA recognition motif.
Article in The EMBO journal, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 126 citations in OpenAlex.
- Remodeling of mRNA by eIF4F in human translation initiation.bioRxiv : the preprint server for biology · 2026Article
- Disordered regions of human eIF4B orchestrate a dynamic self-association landscape.Nature communications · 2024Article
- Article
- Coiled-Coil Motifs of RNA-Binding Proteins: Dynamicity in RNA Regulation.Frontiers in cell and developmental biology · 2020Article
- Article
- Yeast eIF4B binds to the head of the 40S ribosomal subunit and promotes mRNA recruitment through its N-terminal and internal repeat domains.RNA (New York, N.Y.) · 2013Article
- Duplex unwinding and ATPase activities of the DEAD-box helicase eIF4A are coupled by eIF4G and eIF4B.Journal of molecular biology · 2011Article
- eIF4B controls survival and proliferation and is regulated by proto-oncogenic signaling pathways.Cell cycle (Georgetown, Tex.) · 2010Article
- Control of cell survival and proliferation by mammalian eukaryotic initiation factor 4B.Molecular and cellular biology · 2010Article
- Evidence for variation in the optimal translation initiation complex: plant eIF4B, eIF4F, and eIF(iso)4F differentially promote translation of mRNAs.Plant physiology · 2009Article
- Translation initiation factor 4B homodimerization, RNA binding, and interaction with Poly(A)-binding protein are enhanced by zinc.The Journal of biological chemistry · 2008Article
- Interactions between eIF4AI and its accessory factors eIF4B and eIF4H.RNA (New York, N.Y.) · 2008Article
- mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin.The EMBO journal · 2006Article
- Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases.The EMBO journal · 2004Article
- Epstein-barr virus-induced changes in B-lymphocyte gene expression.Journal of virology · 2002Article
- Computational modeling of eukaryotic mRNA turnover.RNA (New York, N.Y.) · 2001Article
- IRES interaction with translation initiation factors: functional characterization of novel RNA contacts with eIF3, eIF4B, and eIF4GII.RNA (New York, N.Y.) · 2001Article
- The RNA recognition motif of yeast translation initiation factor Tif3/eIF4B is required but not sufficient for RNA strand-exchange and translational activity.RNA (New York, N.Y.) · 1998Article
- Ribonuclease E organizes the protein interactions in the Escherichia coli RNA degradosome.Genes & development · 1998Article
- Virus-encoded RNA helicases.Journal of virology · 1997Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Eukaryotic protein synthesis initiation factor 4B (eIF-4B) is an 80,000 dalton polypeptide which is essential for the binding of mRNA to ribosomes. A highly purified preparation of eIF-4B from HeLa cells was subjected to enzymatic cleavage and amino-terminal amino acid sequence analysis. Degenerate oligonucleotide probes were used to isolate a 3851 bp cDNA encoding eIF-4B from a human cDNA library. The DNA encodes a protein comprising 611 residues with a mass of 69,843 daltons. The amino-terminal domain of eIF-4B contains a consensus RNA binding domain present in a number of other RNA binding proteins. Expression of eIF-4B in transfected COS-1 cells yielded a polypeptide which reacted with anti-eIF-4B antiserum and comigrated with purified eIF-4B. Expression of eIF-4B in COS-1 cells resulted in a general inhibition of translation, possibly due to a 50-fold eIF-4B overproduction.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.