ArticleJournal of Korean Neurosurgical Society2013
Cerebral aspergillosis with multiple enhancing nodules in the right cerebral hemisphere in the immune-competent patient.
Article in Journal of Korean Neurosurgical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Intracranial aspergillosis in immunocompetent adult patients without risk factors: a systematic review.Neurosurgical review · 2022Pooled it
- Evolution of neuroimaging findings in angioinvasive cerebral aspergillosis in a pediatric patient with leukemia during long-term observation.BMC infectious diseases · 2023Article
- Long term outcome of medical and surgical co-management of craniospinal aspergillosis in an immunocompromised patient.Medical mycology case reports · 2016Article
- Magnetic Resonance Imaging of Cerebral Aspergillosis: Imaging and Pathological Correlations.PloS one · 2016Article
- Chronic Invasive Aspergillus Sinusitis and Otitis with Meningeal Extension Successfully Treated with Voriconazole.Antimicrobial agents and chemotherapy · 2015Article
- A fatal case of cerebral aspergillosis in a diabetes mellitus patient.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2015Article
- Imaging in Neurologic Infections II: Fungal and Viral Diseases.Current infectious disease reports · 2015Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Aspergillosis in the central nervous system (CNS) is a very rare disease in immune-competent patients. There was a case of a healthy man without a history of immune-compromised disease who had invasive aspergillosis with unusual radiologic findings. A 48-year-old healthy man with diabetes mellitus, presented with complaints of blurred vision that persisted for one month. Brain magnetic resonance imaging (MRI) showed multiple nodular enhancing lesions on the right cerebral hemisphere. The diffusion image appeared in a high-signal intensity in these areas. Cerebrospinal fluid examination did not show any infection signs. An open biopsy was done and intraoperative findings showed grayish inflammatory and necrotic tissue without a definitive mass lesion. The pathologic result was a brain abscess caused by fungal infection, morphologically aspergillus. Antifungal agents (Amphotericin B, Ambisome and Voriconazole) were used for treatment for 3 months. The visual symptoms improved. There was no recurrence or abscess pocket, but the remaining focal enhanced lesions were visible in the right temporal and occipital area at a one year follow-up MRI. This immune-competent patient showed multiple enhancing CNS aspergillosis in the cerebral hemisphere, which had a good outcome with antifungal agents.
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